Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration.

Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration.
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干细胞的生肌分化促进骨骼肌再生

DOI:
10.1155/2021/8884283
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发表时间:
2021
影响因子:
4.3
通讯作者:
Xiao W
Xiao W
中科院分区:
医学3区
文献类型:
--
作者:
Yu D;Cai Z;Li D;Zhang Y;He M;Yang Y;Liu D;Xie W;Li Y;Xiao W

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干细胞具有自我更新和分化的能力,已成为再生医学领域的研究热点。骨骼肌组织是人体最重要的组织之一,严重受损后很难恢复。然而,传统的治疗方法会给患者带来巨大的痛苦。以干细胞为基础的组织工程可以在损伤小的情况下最大程度地修复骨骼肌。因此,干细胞在骨骼肌再生中的应用前景十分广阔。本文就骨骼肌再生的支架材料和干细胞的研究进展进行综述,并对今后的发展提出了自己的看法。
Stem cells have become a hot research topic in the field of regenerative medicine due to their self-renewal and differentiation capabilities. Skeletal muscle tissue is one of the most important tissues in the human body, and it is difficult to recover when severely damaged. However, conventional treatment methods can cause great pain to patients. Stem cell-based tissue engineering can repair skeletal muscle to the greatest extent with little damage. Therefore, the application of stem cells to skeletal muscle regeneration is very promising. In this review, we discuss scaffolds and stem cells for skeletal muscle regeneration and put forward our ideas for future development.
DOI: 10.3390/ma11071116
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期刊: Materials (Basel, Switzerland)
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