Imaging of transplanted islets by positron emission tomography, magnetic resonance imaging, and ultrasonography.
Imaging of transplanted islets by positron emission tomography, magnetic resonance imaging, and ultrasonography.
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作者：
Sakata N;Yoshimatsu G;Tsuchiya H;Aoki T;Mizuma M;Motoi F;Katayose Y;Kodama T;Egawa S;Unno M
虽然胰岛移植被认为是治疗严重糖尿病（DM）的一种有用的治疗选择，但这种治疗的结果仍然不令人满意。这在很大程度上是由于早期移植阶段胰岛的损伤和损失。因此，重要的是监测移植胰岛的状况，以便在需要时选择治疗以拯救胰岛免受损伤。最近，已经进行了许多试验，以研究不同的成像方式可视化移植胰岛的疗效。正电子发射断层扫描（PET）和磁共振成像（MRI）是最常用的成像方式。包括我们在内的一些研究小组也试图通过超声检查（US）来观察移植的胰岛。本文就胰岛成像的最新进展作一综述。
While islet transplantation is considered a useful therapeutic option for severe diabetes mellitus (DM), the outcome of this treatment remains unsatisfactory. This is largely due to the damage and loss of islets in the early transplant stage. Thus, it is important to monitor the condition of the transplanted islets, so that a treatment can be selected to rescue the islets from damage if needed. Recently, numerous trials have been performed to investigate the efficacy of different imaging modalities for visualizing transplanted islets. Positron emission tomography (PET) and magnetic resonance imaging (MRI) are the most commonly used imaging modalities for this purpose. Some groups, including ours, have also tried to visualize transplanted islets by ultrasonography (US). In this review article, we discuss the recent progress in islet imaging.
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