Heterogeneous oxygenation in nonexercising triceps surae muscle during contralateral isometric exercise

Heterogeneous oxygenation in nonexercising triceps surae muscle during contralateral isometric exercise
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对侧等长运动期间非运动小腿三头肌的不均匀氧合

DOI:
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发表时间:
2006
影响因子:
3
通讯作者:
I. Muraoka
I. Muraoka
中科院分区:
医学3区
文献类型:
--
作者:
M. Mizuno;K. Tokizawa;I. Muraoka

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为了测试对侧肌肉静态收缩引起的静息骨骼肌氧合变化在给定骨骼肌内是否均匀,我们使用了近红外光谱(NIRS)。7名受试者在30%的最大随意收缩下进行2 min静态膝关节伸展运动。采用多通道近红外光谱仪(40通道,13个光源,12个探测器)监测对侧非运动小腿三头肌的氧合血红蛋白(HbO 2)变化。HbO 2的变化表示为总不稳定信号的百分比。为了表征HbO 2变化的分布,比较了小腿三头肌上通道的位置,并表示为“近端与远端”和“外侧与内侧”部分。在静态肌肉收缩时,各通道的平均HbO 2变化与小腿血流(体积描记法; R2=0.188,P<0.05)和小腿血管传导(R2=0.146,P<0.05)相关。小腿三头肌的外侧和内侧部分之间的HbO 2没有显着差异。肌近端HbO 2下降幅度大于远端(P<0.05)。这些结果表明,由对侧肌肉的静态收缩引起的静息肌肉的氧合变化是不均匀的。
To test whether changes in oxygenation of a resting skeletal muscle, evoked by a static contraction in a contralateral muscle, is uniform within a given skeletal muscle, we used near-infrared spectroscopy (NIRS). Seven subjects performed 2 min static knee extension exercise at 30% of maximal voluntary contraction. Changes in oxygenated hemoglobin (HbO2) were monitored using multiple-channel NIRS (40 channels, 13 sources and 12 detectors) attached on the contralateral nonexercising triceps surae muscle. Changes in HbO2 were expressed as a percentage of total labile signals. To characterize the distribution of changes in HbO2, channels were compared between their positions on the triceps surae muscle, and represented as ‘proximal versus distal’ and ‘lateral versus medial’ portions. During static muscle contraction, the averaged changes in HbO2 of all channels were correlated with those in calf blood flow (plethysmography; R2=0.188, P<0.05) and with calf vascular conductance (R2=0.146, P<0.05). HbO2 did not differ significantly between the lateral and medial portions of the triceps surae muscle. In contrast, the decrease of HbO2 in the proximal portion of the muscle was greater than that of the distal portion (P<0.05). These results indicate that the changes in oxygenation of a resting muscle, evoked by static contraction of the contralateral muscle, are heterogeneous.
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