Remineralization of human natural caries and artificial caries-like lesions with an experimental whisker-reinforced ART composite.

Remineralization of human natural caries and artificial caries-like lesions with an experimental whisker-reinforced ART composite.
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DOI:
10.1016/j.actbio.2011.01.002
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发表时间:
2011-05
期刊:
影响因子:
9.7
通讯作者:
Dickens SH
Dickens SH
中科院分区:
工程技术1区
文献类型:
--
作者:
Yang B;Flaim G;Dickens SH

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比较新型晶须增强实验复合树脂与树脂改性玻璃离子水门汀(RM-GIC)对人天然龋和人工龋样牙本质病变的修复作用。制备了10颗中度自然牙本质龋的磨牙(N)。在10个无龋磨牙的咬合牙本质中制备人工龋样牙本质损伤,并在pH=4.3下脱矿48 h(A)。用ART复合材料或RM-GIC修复。将所有修复牙切成120 μm的切片。采用X线片结合数字图像分析技术,分析去矿化/去矿化处理前、4周和8周后标本同一部位的骨密度变化。4周和8周后的平均再矿化百分比±标准差为:N:ART-复合:27±9,46±14; RM-GIC:18±6,36±11; A:ART-复合:48±9,66±11; RM-GIC:50±13,62±11。对于自然龋的再矿化,ART-复合材料与RM-GIC之间有显著性差异(p<0.05)。两种充填剂对天然龋和人工龋的矿化度有显著性差异(P<0.001)。ART复合材料和RM-GIC对天然龋和人工龋的修复效果不同,这很可能是由于龋牙本质的微观结构和组成不同。
To compare the remineralization of human natural caries and artificial caries-like dentin lesions from a novel whisker-reinforced experimental composite resin to a resin-modified glass ionomer cement (RM-GIC) as control. Ten molars with moderate natural dentin caries were prepared (N). Artificial caries-like dentin lesions were prepared in occlusal dentin of ten caries-free molars and demineralized at pH=4.3 for 48 h (A). The cavities were restored with ART-composite or RM-GIC. All restored teeth were sliced into 120-μm sections. Transverse microradiography combined with digital image analysis was performed to analyze the change in mineral density at the same position of the specimens before, after 4 weeks and 8 weeks remineralization/demineralization treatment. The mean percent remineralization ± standard deviation after 4 weeks and 8 weeks are: N: ART-composite: 27±9, 46±14; RM-GIC: 18±6, 36±11; A: ART-composite: 48±9, 66±11; RM-GIC: 50±13, 62±11. For the remineralization of natural caries, there was a significant difference between ART-composite and RM-GIC (p<0.05). For both restoratives there were significant differences between remineralization of natural and artificial caries (p<0.001). ART-composite and RM-GIC remineralized natural and artificial caries differently most likely due to differences in microstructure and composition of caries dentin.
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