Restrictive Eating Disorders and Skeletal Health in Adolescent Girls and Young Women.
Restrictive Eating Disorders and Skeletal Health in Adolescent Girls and Young Women.
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DOI：
10.1007/s00223-016-0164-0
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发表时间：
2017-05
影响因子：
4.2
通讯作者：
Gordon, Catherine M.
中科院分区：
文献类型：
--
作者：
Thornton, Darcey;Gordon, Catherine M.
本文综述了限制性进食障碍对骨骼健康的影响。饮食失调和闭经之间的关系进行了详细讨论。营养不良对骨的病理影响是通过检查各种可用的成像技术的研究结果来探讨的。本文综述了神经性厌食症青少年和年轻女性的多种激素变化，以及这些变化如何影响骨转换、密度、结构和强度。青少年和年轻女性与这些疾病的诊断临床评价概述。从临床和机制的角度考虑现有的治疗方案，包括那些有希望的疗效，以及我们认为是无效的。最后，提供了未来的研究机会，包括脂肪和骨骼相互作用领域的有趣工作。
This article reviews the effects of restrictive eating disorders on bone health. The relationship between eating disorders and amenorrhea is discussed in detail. The pathologic impact of malnutrition on bone is explored by examining the results of studies using various available imaging techniques. The multiple hormonal alterations seen in adolescents and young women with anorexia nervosa are reviewed, and how these alterations may influence bone turnover, density, structure and strength. The diagnostic clinical evaluation for adolescents and young women with these disorders is outlined. Available treatment options, including those that hold promise for efficacy, as well we those deemed to be ineffective, are considered from both a clinical and mechanistic standpoint. Finally, future research opportunities are offered, including intriguing work in the area of fat and bone interactions.
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影响因子：
1.8
作者：
dos Santos, Evaldo;dos Santos, Jose E.;Silva de Sa, Marcos F.
通讯作者：
Silva de Sa, Marcos F.
DOI：
10.1359/jbmr.090805
发表时间：
2010-02
期刊：
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
影响因子：
--
作者：
Ecklund K;Vajapeyam S;Feldman HA;Buzney CD;Mulkern RV;Kleinman PK;Rosen CJ;Gordon CM
通讯作者：
Gordon CM
影响因子：
29
作者：
Della Torre, Sara;Rando, Gianpaolo;Maggi, Adriana
通讯作者：
Maggi, Adriana
影响因子：
2.7
作者：
Clarke, Bart L.;Khosla, Sundeep
通讯作者：
Khosla, Sundeep
影响因子：
5.8
作者：
BACHRACH, LK;KATZMAN, DK;MARCUS, R
通讯作者：
MARCUS, R