The future of ultra-high field MRI and fMRI for study of the human brain.

The future of ultra-high field MRI and fMRI for study of the human brain.
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DOI:
10.1016/j.neuroimage.2011.10.065
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发表时间:
2012-08-15
期刊:
影响因子:
5.7
通讯作者:
Duyn, Jeff H.
Duyn, Jeff H.
中科院分区:
医学1区
文献类型:
--
作者:
Duyn, Jeff H.

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核磁共振成像和功能性核磁共振成像已经分别使用了30年和20年,在这段时间里,无论是在数据质量还是在研究大脑的应用范围上,都发生了很大的变化。除了分辨率从早期的4 mm左右提高到现代技术的0.5 mm以下之外,对比度的新用途已经导致能够在细胞尺度上使图像敏感于大脑的一些结构特性,以及在皮质柱水平上研究大脑功能的定位和组织。这些发展在一定程度上是由于不断增加磁场强度的推动。在未来的几十年里,我们会看到类似的进步吗?在这里,我们将讨论高场MRI的当前状态,预期进一步增加场强,以及预期随着这些增加而改善。
MRI and fMRI have been used for about three and two decades respectively and much has changed over this time period, both in the quality of the data and in the range of applications for studying the brain. Apart from resolution improvements from around 4 mm in the early days to below 0.5 mm with modern technology, novel uses of contrast have led to the ability to sensitize images to some of the brain’s structural properties at the cellular scale as well as study the localization and organization of brain function at the level of cortical columns. These developments have in part been facilitated by a continuing drive to increase the magnetic field strength. Will the next few decades see similar improvements? Here we will discuss current state of high field MRI, expected further increases in field strength, and improvements expected with these increases.
使用 7 特斯拉磁共振成像直接可视化帕金森病的深部脑刺激目标。
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