Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China.
Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China.
复制标题
DOI：
10.1080/21645515.2022.2043025
复制
发表时间：
2022-11-30
影响因子：
4.8
通讯作者：
中科院分区：
文献类型：
--
作者：
鉴于全球对疫苗接种迟疑的担忧与日俱增，本研究估计了强制疫苗和非强制疫苗在儿童中的覆盖率，并评估了年轻父母的疫苗迟疑是否与他们的孩子ʻS最终在上海接种疫苗的状况有关。在上海的一项队列研究中，中国，我们查明了幼儿父母对疫苗接种的犹豫，后来提取了他们的孩子ʻS的电子免疫记录。我们在强制性和公共资助的扩大免疫计划(EPI)上衡量疫苗的全覆盖。非计划免疫疫苗包括肺炎球菌结合疫苗、b型流感嗜血杆菌疫苗和轮状病毒疫苗。疫苗迟疑通过混合效应Logistic回归模型与疫苗接种率有关。在972名儿童中，到15个 月时，所有计划免疫疫苗的完全覆盖率为95%，相比之下，肺炎球菌结合疫苗的第一剂覆盖率为13%，b型流感嗜血杆菌疫苗的覆盖率为68%，轮状病毒疫苗的覆盖率为52%。疫苗迟疑与所有计划免疫疫苗的完全覆盖没有显著关联(OR：1.55，95%CI：.89，2.72)，但肺炎球菌结合疫苗1剂(OR：.70，95%CI：.53，.91)和轮状病毒疫苗1剂(OR：.69，95%CI：.56，.86)的疫苗迟疑覆盖率较低。在计划免疫疫苗中，不同教育水平的差异不显著，但在肺炎球菌结合疫苗和轮状病毒疫苗的第一剂中差异显著。总体而言，疫苗迟疑与非计划免疫疫苗的摄取率较低有关，但与计划免疫疫苗无关。上海有一个健全的制度，为公平获得计划免疫疫苗提供保险，但如果疫苗接种犹豫不决，可能会减少非计划免疫疫苗的覆盖范围。
Given increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their childʻs eventual vaccination status in Shanghai, China. In a cohort study within Shanghai, China, we ascertained vaccine hesitancy among parents of young infants, and later abstracted their childʻs electronic immunization records. We measure full coverage of vaccines on the mandatory, and publicly funded Expanded Program on Immunization (EPI). Non-EPI vaccines included pneumococcal conjugate vaccine, Haemophilus influenzae type b vaccine, and rotavirus vaccine. Vaccine hesitancy was linked to vaccine uptake through mixed effects logistic regression models. Among 972 children, full coverage of all EPI vaccines by 15 months was 95%, compared to dose 1 coverage of pneumococcal conjugate vaccine at 13%, Haemophilus influenzae type b vaccine at 68%, and rotavirus vaccine at 52%. Vaccine hesitancy was not significantly linked with full coverage of all EPI vaccines (OR: 1.55, 95% CI: .89, 2.72), but coverage in the vaccine hesitant was lower for pneumococcal conjugate vaccine dose 1 (OR: .70, 95% CI: .53, .91), and rotavirus vaccine dose 1 (OR: .69, 95% CI: .56, .86). Disparities by education level were not significant for EPI vaccines, but were for dose 1 of pneumococcal conjugate vaccine rotavirus vaccine. Overall, vaccine hesitancy was related to lower uptake of non-EPI, but not EPI vaccines. Shanghai has a robust system for insurance equitable access to EPI vaccines, but if vaccine hesitancy grows, it could reduce coverage of non-EPI vaccines.
登录
查看更多内容
影响因子：
5.5
作者：
Wagner, Abram L.;Boulton, Matthew L.;Zikmund-Fisher, Brian J.
通讯作者：
Zikmund-Fisher, Brian J.
DOI：
10.15585/mmwr.mm6945a7
发表时间：
2020-11-13
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Chard AN;Gacic-Dobo M;Diallo MS;Sodha SV;Wallace AS
通讯作者：
Wallace AS
影响因子：
5.5
作者：
Cui, Fuqiang;Liang, Xiaofeng;Yang, Weizhong
通讯作者：
Yang, Weizhong
影响因子：
2.4
作者：
Wagner AL;Boulton ML;Sun X;Mukherjee B;Huang Z;Harmsen IA;Ren J;Zikmund-Fisher BJ
通讯作者：
Zikmund-Fisher BJ
影响因子：
5.5
作者：
Hou, Zhiyuan;Chang, Jie;Zhang, Yuting
通讯作者：
Zhang, Yuting