Host-Multi-Pathogen Warfare: Pathogen Interactions in Co-infected Plants.
Host-Multi-Pathogen Warfare: Pathogen Interactions in Co-infected Plants.
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DOI：
10.3389/fpls.2017.01806
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发表时间：
2017
影响因子：
5.6
通讯作者：
Zerihun A
中科院分区：
文献类型：
--
作者：
Abdullah AS;Moffat CS;Lopez-Ruiz FJ;Gibberd MR;Hamblin J;Zerihun A
植物-病原体相互作用的研究历来集中在涉及单宿主-单病害系统的简单感染模型上。然而，植物感染通常涉及多个物种和/或基因型，并表现出在单一宿主-单一疾病系统中无法捕获的复杂性。在这里，我们回顾了最近的见解，共感染系统，重点是宿主多病原体相互作用的动态和宿主易感性/抗性的影响。在合并感染系统中，病原体相互作用包括：㈠竞争，即相互竞争的病原体形成物理屏障或利用毒素将竞争者排除在资源密集的生态位之外; ㈡合作，即病原体通过提供发病所必需的相互生化信号或通过交换生存所需资源实现功能互补而进行有益的相互作用; ㈢共存，即病原体可以通过生态位专门化稳定共存。此外，宿主还能够主动或被动地通过针对至少一种病原体的防御反应来调节生态位竞争。然而，通常，有毒病原体破坏宿主防御以促进感染，并且由一种病原体引起的反应可以在另一种病原体存在的情况下被改变。也有证据表明，虽然罕见，病原体纳入外源基因，扩大生态位适应和提高毒力。在整个审查中，我们借鉴了一系列病原体类型的共感染系统的例子，并确定了未来疾病控制策略创新的突出问题。
Studies of plant–pathogen interactions have historically focused on simple models of infection involving single host-single disease systems. However, plant infections often involve multiple species and/or genotypes and exhibit complexities not captured in single host-single disease systems. Here, we review recent insights into co-infection systems focusing on the dynamics of host-multi-pathogen interactions and the implications for host susceptibility/resistance. In co-infection systems, pathogen interactions include: (i) Competition, in which competing pathogens develop physical barriers or utilize toxins to exclude competitors from resource-dense niches; (ii) Cooperation, whereby pathogens beneficially interact, by providing mutual biochemical signals essential for pathogenesis, or through functional complementation via the exchange of resources necessary for survival; (iii) Coexistence, whereby pathogens can stably coexist through niche specialization. Furthermore, hosts are also able to, actively or passively, modulate niche competition through defense responses that target at least one pathogen. Typically, however, virulent pathogens subvert host defenses to facilitate infection, and responses elicited by one pathogen may be modified in the presence of another pathogen. Evidence also exists, albeit rare, of pathogens incorporating foreign genes that broaden niche adaptation and improve virulence. Throughout this review, we draw upon examples of co-infection systems from a range of pathogen types and identify outstanding questions for future innovation in disease control strategies.
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影响因子：
3.2
作者：
ADEE, SR;PFENDER, WF;HARTNETT, DC
通讯作者：
HARTNETT, DC
影响因子：
2.7
作者：
Al-Naimi, FA;Garrett, KA;Bockus, WW
通讯作者：
Bockus, WW
影响因子：
11.4
作者：
de Torres-Zabala, Marta;Truman, William;Grant, Murray
通讯作者：
Grant, Murray
DOI：
10.1073/pnas.0500078102
发表时间：
2005-05-24
影响因子：
11.1
作者：
de Roode, JC;Pansini, R;Read, AF
通讯作者：
Read, AF
影响因子：
3.5
作者：
Aime, Sebastien;Alabouvette, Claude;Olivain, Chantal
通讯作者：
Olivain, Chantal