Perspective: Is the Response of Human Energy Expenditure to Increased Physical Activity Additive or Constrained?

Perspective: Is the Response of Human Energy Expenditure to Increased Physical Activity Additive or Constrained?
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DOI:
10.1016/j.advnut.2023.02.003
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发表时间:
2023-05
期刊:
Advances in nutrition (Bethesda, Md.)
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增加体力活动直接增加人类 TEE(加性模型)的观点受到能量约束假说(约束模型)的挑战。该模型提出,增加体力活动会减少新陈代谢的其他组成部分,从而限制 TEE。新陈代谢的权衡有一个逻辑进化论,但迄今为止,支持约束的证据受到一些限制,包括横断面和相关性研究,其中包括身体尺寸/成分和生活方式极端差异带来的潜在方法学问题、回归稀释和虚假相关等潜在统计问题,以及从演绎推理而不是直接观察补偿中得出的结论。为了在未来的研究中解决这些局限性,理想情况下,随机对照试验应该提高人类能量消耗模型的准确性。现有证据表明,在许多情况下,增加体力活动对 TEE 的影响大部分是累加性的,尽管有些能量似乎“消失”且目前下落不明。能量平衡的程度可以进一步缓和这种影响。
The idea that increasing physical activity directly adds to TEE in humans (additive model) has been challenged by the energy constrained hypothesis (constrained model). This model proposes that increased physical activity decreases other components of metabolism to constrain TEE. There is a logical evolutionary argument for trade-offs in metabolism, but, to date, evidence supporting constraint is subject to several limitations, including cross-sectional and correlational studies with potential methodological issues from extreme differences in body size/composition and lifestyle, potential statistical issues such as regression dilution and spurious correlations, and conclusions drawn from deductive inference rather than direct observation of compensation. Addressing these limitations in future studies, ideally, randomized controlled trials should improve the accuracy of models of human energy expenditure. The available evidence indicates that in many scenarios, the effect of increasing physical activity on TEE will be mostly additive although some energy appears to “go missing” and is currently unaccounted for. The degree of energy balance could moderate this effect even further.
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