A CMOS Time-Resolved Fluorescence Lifetime Analysis Micro-System.
A CMOS Time-Resolved Fluorescence Lifetime Analysis Micro-System.
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DOI:
10.3390/s91109255
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发表时间:
2009
期刊:
影响因子:
--
通讯作者:
Henderson RK
中科院分区:
文献类型:
--
作者:
Rae BR;Muir KR;Gong Z;McKendry J;Girkin JM;Gu E;Renshaw D;Dawson MD;Henderson RK
We describe a CMOS-based micro-system for time-resolved fluorescence lifetime analysis. It comprises a 16 × 4 array of single-photon avalanche diodes (SPADs) fabricated in 0.35 μm high-voltage CMOS technology with in-pixel time-gated photon counting circuitry and a second device incorporating an 8 × 8 AlInGaN blue micro-pixellated light-emitting diode (micro-LED) array bump-bonded to an equivalent array of LED drivers realized in a standard low-voltage 0.35 μm CMOS technology, capable of producing excitation pulses with a width of 777 ps (FWHM). This system replaces instrumentation based on lasers, photomultiplier tubes, bulk optics and discrete electronics with a PC-based micro-system. Demonstrator lifetime measurements of colloidal quantum dot and Rhodamine samples are presented.
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