Haemophilus influenzae infections in adults: characterization of strains by serotypes, biotypes, and beta-lactamase production.
Haemophilus influenzae infections in adults: characterization of strains by serotypes, biotypes, and beta-lactamase production.
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成人流感嗜血杆菌感染:按血清型、生物型和 β-内酰胺酶产生来表征菌株。
DOI:
10.1093/infdis/144.2.101
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发表时间:
1981
期刊:
影响因子:
--
通讯作者:
Trier,PA
中科院分区:
文献类型:
--
作者:
WallaceJr,RJ;Musher,DM;Septimus,EJ;McGowanJr,JE;Quinones,FJ;Wiss,K;Vance,PH;Trier,PA
One hundred three cases of bacteremia or meningitis due toHaemophilus influenzaein adults were evaluated. Among 96 episodes of bacteremia, 60% were due to pneumonia and 15% to genital-related infections; 10% had no apparent source of infection. Of 42 isolates serotyped in routine fashion by slide agglutination, 79% were reported as type b. In contrast, of 45 isolates from the same interval with confirmed serotyping (usually by counterimmunoelectrophoresis), only 29% were type band 64% were nontypable; 26% had been misidentified by routine slide agglutination. The majority (85%) of confirmed typable strains were biotype I. Four (40%) of 10 nontypable obstetrical isolates belonged to the relativelyrare biotype IV. Only2% of isolates wereampicillin-resistant, despite a high resistance rate among pediatric isolates in the same communities. When serotyping is carefully performed, nontypable organisms appear to be the major cause of invasiveH. influenzaedisease in adults.
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