Nutritional interventions or exposures in infants and children aged up to 3 years and their effects on subsequent risk of overweight, obesity and body fat: a systematic review of systematic reviews
Nutritional interventions or exposures in infants and children aged up to 3 years and their effects on subsequent risk of overweight, obesity and body fat: a systematic review of systematic reviews
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婴儿和 3 岁以下儿童的营养干预或暴露及其对随后超重、肥胖和身体脂肪风险的影响：系统评价的系统评价
DOI：
10.1111/obr.12745
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发表时间：
2018
期刊：
影响因子：
8.9
通讯作者：
Patro-Golab B
中科院分区：
文献类型：
--
作者：
Patro-Golab B
本研究作为国际早期营养研究项目的一部分，对儿童（3岁以下）营养干预或暴露对随后肥胖、超重和肥胖风险的影响进行了系统评价。检索了截至2015年9月的电子数据库（包括MEDLINE、EMBASE和科克伦图书馆）。纳入了40篇系统评价。母乳喂养与儿童和成年期超重和肥胖风险的适度降低之间存在一致的关联（基于高质量研究，几率降低了13%），但不能排除残余混杂因素。降低婴儿配方奶粉的蛋白质含量是一种有希望的干预措施，可以降低儿童日后超重和肥胖的风险。没有一致的证据表明，在儿童早期引入补充食品、含糖饮料或能量摄入的年龄与后来的超重/肥胖有关，但有一些迹象表明，在补充喂养期间蛋白质摄入与后来的超重/肥胖有关。没有足够的证据来确定其他营养干预或暴露的影响，包括婴儿配方奶粉成分的改变，脂肪摄入或不同食物组的消费。
This study, performed as part of the international EarlyNutrition research project, provides a systematic review of systematic reviews on the effects of nutritional interventions or exposures in children (up to three years of age) on the subsequent risk of obesity, overweight, and adiposity. Electronic databases (including MEDLINE, EMBASE, and Cochrane Library) were searched up until September 2015. Forty systematic reviews were included. A consistent association of breastfeeding with a modest reduction in the risk of later overweight and obesity in childhood and adulthood was found (the odds decreased by 13% based on high quality studies), but residual confounding cannot be excluded. Lowering the protein content of infant formula is a promising intervention to reduce the risk of later overweight and obesity in children. There is no consistent evidence of an association of the age of introducing complementary foods, sugar-sweetened beverage, or energy intake in early childhood, with later overweight/obesity, but there are some indications of an association of protein intake during the complementary feeding period with later overweight/obesity. There was inadequate evidence to determine effects of other nutritional interventions or exposures, including modifications of infant formula composition, fat intake or consumption of different food groups.
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10.1093/jn/132.8.2127
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