Rates of respiratory syncytial virus (RSV)-associated hospitalization among adults with congestive heart failure-United States, 2015-2017.
Rates of respiratory syncytial virus (RSV)-associated hospitalization among adults with congestive heart failure-United States, 2015-2017.
复制标题
DOI：
10.1371/journal.pone.0264890
复制
发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Kim L
中科院分区：
文献类型：
--
作者：
Kujawski SA;Whitaker M;Ritchey MD;Reingold AL;Chai SJ;Anderson EJ;Openo KP;Monroe M;Ryan P;Bye E;Como-Sabetti K;Barney GR;Muse A;Bennett NM;Felsen CB;Thomas A;Crawford C;Talbot HK;Schaffner W;Gerber SI;Langley GE;Kim L
呼吸道合胞病毒（RSV）可导致患有心肺疾病的成年人患上严重疾病，例如充血性心力衰竭（CHF）。我们在美国使用基于人群的监测方法，根据CHF状态量化了成人RSV相关住院率。在10月1日至4月30日的两个呼吸季节（2015-2017年）期间，在7个地点的35个县进行了基于人群的RSV监测（RSV-NET）。纳入了监测集水区内入院的成人（≥18岁），这些成人经临床医生指导的检测发现实验室确认的RSV。通过病历提取确定是否存在基础CHF。我们根据CHF状态计算总体和年龄分层（<65岁和≥65岁）RSV相关住院率。估计值根据年龄和RSV检测不足进行调整。我们还报告率差（RD）和率比（RR），通过比较率与CHF。确定了记录的2042例CHF状态的住院RSV病例。大多数（60.2%，n = 1230）年龄≥65岁，28.3%（n = 577）患有CHF。CHF成人中校正的RSV住院率为26.7（95% CI：22.2，31.8）/10，000人，而非CHF成人中为3.3（95% CI：3.3，3.3）/10，000人（RR：8.1，95% CI：6.8，9.7; RD：23.4，95% CI：18.9，28.5）。CHF成人患者在两个年龄组（<65岁和≥65岁）中RSV相关住院率较高。年龄≥65岁的成人CHF发生率最高（40.5/10，000人群，95% CI：35.1，46.6）。CHF成人患者RSV相关住院率是非CHF成人患者的8倍。识别RSV感染的高风险人群可以为未来的RSV疫苗接种政策和建议提供信息。
Respiratory syncytial virus (RSV) can cause severe disease in adults with cardiopulmonary conditions, such as congestive heart failure (CHF). We quantified the rate of RSV-associated hospitalization in adults by CHF status using population-based surveillance in the United States. Population-based surveillance for RSV (RSV-NET) was performed in 35 counties in seven sites during two respiratory seasons (2015–2017) from October 1–April 30. Adults (≥18 years) admitted to a hospital within the surveillance catchment area with laboratory-confirmed RSV identified by clinician-directed testing were included. Presence of underlying CHF was determined by medical chart abstraction. We calculated overall and age-stratified (<65 years and ≥65 years) RSV-associated hospitalization rates by CHF status. Estimates were adjusted for age and the under-detection of RSV. We also report rate differences (RD) and rate ratios (RR) by comparing the rates for those with and without CHF. 2042 hospitalized RSV cases with CHF status recorded were identified. Most (60.2%, n = 1230) were ≥65 years, and 28.3% (n = 577) had CHF. The adjusted RSV hospitalization rate was 26.7 (95% CI: 22.2, 31.8) per 10,000 population in adults with CHF versus 3.3 (95% CI: 3.3, 3.3) per 10,000 in adults without CHF (RR: 8.1, 95% CI: 6.8, 9.7; RD: 23.4, 95% CI: 18.9, 28.5). Adults with CHF had higher rates of RSV-associated hospitalization in both age groups (<65 years and ≥65 years). Adults ≥65 years with CHF had the highest rate (40.5 per 10,000 population, 95% CI: 35.1, 46.6). Adults with CHF had 8 times the rate of RSV-associated hospitalization compared with adults without CHF. Identifying high-risk populations for RSV infection can inform future RSV vaccination policies and recommendations.
登录
查看更多内容
DOI：
10.1093/infdis/jit839
发表时间：
2014-06-15
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
Falsey AR;McElhaney JE;Beran J;van Essen GA;Duval X;Esen M;Galtier F;Gervais P;Hwang SJ;Kremsner P;Launay O;Leroux-Roels G;McNeil SA;Nowakowski A;Richardus JH;Ruiz-Palacios G;St Rose S;Devaster JM;Oostvogels L;Durviaux S;Taylor S
通讯作者：
Taylor S
DOI：
10.3109/15412555.2012.744741
发表时间：
2013-06-01
影响因子：
2.2
作者：
Mehta, Jyotsna;Walsh, Edward E.;Falsey, Ann R.
通讯作者：
Falsey, Ann R.
DOI：
10.1056/nejmoa0804877
发表时间：
2009-02-05
期刊：
The New England journal of medicine
影响因子：
--
作者：
Hall CB;Weinberg GA;Iwane MK;Blumkin AK;Edwards KM;Staat MA;Auinger P;Griffin MR;Poehling KA;Erdman D;Grijalva CG;Zhu Y;Szilagyi P
通讯作者：
Szilagyi P
影响因子：
12.7
作者：
Falsey, Ann R.;Walsh, Edward E.;Griffin, M. Pam
通讯作者：
Griffin, M. Pam
影响因子：
3.7
作者：
McClure DL;Kieke BA;Sundaram ME;Simpson MD;Meece JK;Sifakis F;Gasser RA Jr;Belongia EA
通讯作者：
Belongia EA