γδ T cell and other immune cells crosstalk in cellular immunity.

γδ T cell and other immune cells crosstalk in cellular immunity.
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细胞免疫中的 γ δ T 细胞和其他免疫细胞的串扰

DOI:
10.1155/2014/960252
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发表时间:
2014
影响因子:
4.1
通讯作者:
Huang H
Huang H
中科院分区:
医学3区
文献类型:
--
作者:
He Y;Wu K;Hu Y;Sheng L;Tie R;Wang B;Huang H

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γδT细胞是细胞免疫中具有免疫调节功能的效应细胞。这些能力使它们能够与其他免疫细胞相互作用,从而有可能通过过继细胞疗法治疗各种免疫介导性疾病。到目前为止,γδT细胞与其他免疫细胞之间的相互作用还没有很好的定义。在这里,我们将讨论它们之间的相互作用,并可以想象γδT细胞在免疫治疗中的应用前景。从免疫病理学的角度了解免疫细胞间的相互作用,有助于γδT细胞的临床应用。
γδ T cells have been recognized as effectors with immunomodulatory functions in cellular immunity. These abilities enable them to interact with other immune cells, thus having the potential for treatment of various immune-mediated diseases with adoptive cell therapy. So far, the interactions between γδ T cell and other immune cells have not been well defined. Here we will discuss the interactivities among them and the perspective on γδ T cells for their use in immunotherapy could be imagined. The understanding of the crosstalk among the immune cells in immunopathology might be beneficial for the clinical application of γδ T cell.
证据表明CD8+树突状细胞能够开发调节气道高反应性的γT细胞。
DOI: 10.4049/jimmunol.181.1.309
发表时间: 2008-07-01
影响因子: 4.4
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