Variability of Betweenness Centrality and Its Effect on Identifying Essential Genes.
Variability of Betweenness Centrality and Its Effect on Identifying Essential Genes.
复制标题
中间性中心的变异性及其对识别基本基因的影响。
DOI:
10.1007/s11538-018-0526-z
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发表时间:
2019-09
影响因子:
3.5
通讯作者:
Radunskaya A
中科院分区:
文献类型:
--
作者:
Durón C;Pan Y;Gutmann DH;Hardin J;Radunskaya A
This paper begins to build a theoretical framework that would enable the pharmaceutical industry to use network complexity measures as a way to identify drug targets. The variability of a betweenness measure for a network node is examined through different methods of network perturbation. Our results indicate a robustness of betweenness centrality in the identification of target genes.
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影响因子:
5.2
作者:
Madhavan, Subha;Zenklusen, Jean-Claude;Kotliarov, Yuri;Sahni, Himanso;Fine, Howard A.;Buetow, Kenneth
通讯作者:
Buetow, Kenneth
DOI:
10.1093/bioinformatics/btw216
发表时间:
2016-07-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Lachmann A;Giorgi FM;Lopez G;Califano A
通讯作者:
Califano A
影响因子:
5.3
作者:
Jakovcevski, I;Zecevic, N
通讯作者:
Zecevic, N
影响因子:
3.7
作者:
Pan, Yuan;Duron, Christina;Hardin, Johanna
通讯作者:
Hardin, Johanna
影响因子:
64.8
作者:
Jeong, H;Mason, SP;Oltvai, ZN
通讯作者:
Oltvai, ZN