The double array of filaments in cross-striated muscle.

The double array of filaments in cross-striated muscle.
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DOI:
10.1083/jcb.3.5.631
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发表时间:
1957-09-25
期刊:
The Journal of biophysical and biochemical cytology
影响因子:
--
通讯作者:
HUXLEY HE
HUXLEY HE
中科院分区:
其他
文献类型:
--
作者:
HUXLEY HE

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在何种条件下,人们可能会期望看到次级丝(如果它们存在)在横纹肌的纵切面,进行了讨论。结果表明,这些条件不满足以前发表的作品,截面太厚。当用适当的薄切片检查时,次级细丝可以非常容易地看到。还可以清楚地看到结构的其他细节,特别是初级和次级细丝之间的交叉桥,以及初级细丝在其末端的锥形。纤维的排列以及与收缩和拉伸相关的变化与从以前的观察中已经推导出的以及在以前的论文中用交叉纤维模型描述的那些是相同的。因此,有充分的理由相信这一模式是正确的。已经提出的替代模型似乎与目前的观察和许多其他现有证据都不一致。
The conditions under which one might expect to see the secondary filaments (if they exist) in longitudinal sections of striated muscle, are discussed. It is shown that these conditions were not satisfied in previously published works for the sections were too thick. When suitably thin sections are examined, the secondary filaments can be seen perfectly easily. It is also possible to see clearly other details of the structure, notably the cross-bridges between primary and secondary filaments, and the tapering of the primary filaments at their ends. The arrangement of the filaments and the changes associated with contraction and with stretch are identical to those already deduced from previous observations and described in terms of the interdigitating filament model in previous papers. There are therefore excellent grounds for believing that this model is correct. The alternative models which have been proposed appear to be incompatible both with the present observations and with much of the other available evidence.
DOI: 10.1084/jem.99.2.201
发表时间: 1954-01-01
影响因子: 15.3
作者:
HODGE, AJ;HUXLEY, HE;SPIRO, D
通讯作者: SPIRO, D
DOI: 10.1016/0006-3002(53)90156-5
发表时间: 1953-01-01
期刊: BIOCHIMICA ET BIOPHYSICA ACTA
影响因子: --
作者:
HUXLEY, HE
通讯作者: HUXLEY, HE
DOI: 10.1016/0006-3002(55)90235-3
发表时间: 1955-01-01
期刊: BIOCHIMICA ET BIOPHYSICA ACTA
影响因子: --
作者:
SZENTGYORGYI, AG;MAZIA, D;SZENTGYORGYI, A
通讯作者: SZENTGYORGYI, A
DOI: 10.1083/jcb.2.4.143
发表时间: 1956-01-01
期刊: JOUR BIOPHYS AND BIOCHEM CYTOL
影响因子: --
作者:
EDWARDS, GEORGE A.;RUSKA, HELMUT;VALLEJO-FREIRE, ARISTIDES
通讯作者: VALLEJO-FREIRE, ARISTIDES
DOI: 10.1038/172530b0
发表时间: 1953-01-01
期刊: NATURE
影响因子: 64.8
作者:
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通讯作者: HUXLEY, HE