ClusterMine360: a database of microbial PKS/NRPS biosynthesis.

ClusterMine360: a database of microbial PKS/NRPS biosynthesis.
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clustermine360:微生物PKS/NRPS生物合成的数据库。

DOI:
10.1093/nar/gks993
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发表时间:
2013-01
影响因子:
14.9
通讯作者:
Boddy CN
Boddy CN
中科院分区:
生物学2区
文献类型:
--
作者:
Conway KR;Boddy CN

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ClusterMine360(http://www.clustermine360.ca/)是一个微生物聚酮和非核糖体肽基因簇的数据库。它利用众包的优势,允许社区成员做出贡献,同时使用自动化来帮助实现高数据一致性和质量。该数据库目前拥有来自185个化合物家族的200个基因簇。它还具有一个独特的序列储存库,其中包含>10000个聚酮合成酶/非核糖体多肽合成酶结构域。这些序列可以作为单个或多个序列FASTA文件进行过滤和下载。我们相信,这个数据库将成为聚酮合成酶/非核糖体肽合成酶研究社区成员的有用资源,使他们能够跟上不断增长的已测序基因簇的数量,并快速挖掘这些簇以获取功能信息。
ClusterMine360 (http://www.clustermine360.ca/) is a database of microbial polyketide and non-ribosomal peptide gene clusters. It takes advantage of crowd-sourcing by allowing members of the community to make contributions while automation is used to help achieve high data consistency and quality. The database currently has >200 gene clusters from >185 compound families. It also features a unique sequence repository containing >10 000 polyketide synthase/non-ribosomal peptide synthetase domains. The sequences are filterable and downloadable as individual or multiple sequence FASTA files. We are confident that this database will be a useful resource for members of the polyketide synthases/non-ribosomal peptide synthetases research community, enabling them to keep up with the growing number of sequenced gene clusters and rapidly mine these clusters for functional information.
DOI: 10.1093/nar/gkh359
发表时间: 2004-07-01
影响因子: 14.9
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