Electrospun PLGA/multi-walled carbon nanotubes/wool keratin composite membranes: morphological, mechanical, and thermal properties, and their bioactivities in vitro
Electrospun PLGA/multi-walled carbon nanotubes/wool keratin composite membranes: morphological, mechanical, and thermal properties, and their bioactivities in vitro
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电纺PLGA/多壁碳纳米管/羊毛角蛋白复合膜：形态、力学、热性能及其体外生物活性
DOI：
10.1007/s10965-013-0329-8
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发表时间：
2014-01
期刊：
影响因子：
--
通讯作者：
Jinsong Liu
中科院分区：
文献类型：
--
作者：
Hualin Zhang;Juan Wang;Na Yu;Jinsong Liu
本工作以PLGA、多壁碳纳米管(MWNTs)和羊毛角蛋白为原料，通过电纺法制备了一系列PLGA/MWNTs/羊毛角蛋白复合膜。用扫描电子显微镜、透射电子显微镜、热重分析、拉伸测试和X射线衍射仪对杂化纤维的形态、结构、力学性能、热性能和生物活性进行了表征。透射电子显微镜结果表明，多壁碳纳米管和羊毛角蛋白颗粒有效地结合在复合纤维中。MWNTs的加入显著提高了复合材料的力学性能。PLGA/MWNTs/2.0%羊毛角蛋白复合材料具有最佳的极限强度、断裂伸长率和杨氏模量值。PLGA/MWNTs/羊毛角蛋白复合材料均表现出较高的热稳定性和热氧化稳定性。矿化后，磷灰石晶体沉积在PLGA/MWNTs/羊毛角蛋白膜上，表明该复合材料具有较高的生物活性。因此，这些新型的三元PLGA/MWNTs/羊毛角蛋白膜具有很大的潜力来满足GBR膜的需求。
In this work, PLGA, multi-walled carbon nanotubes (MWNTs), and wool keratin were successfully electrospun to generate a series of PLGA/MWNTs/wool keratin membranes. The morphologies, structures, mechanical properties, thermal properties, and bioactivities of the resulting hybrid fibers were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermo-gravimetric analysis (TGA), tensile testing, and X-ray diffraction (XRD). The TEM results confirmed that the MWNTs and wool keratin particles were effectively incorporated into the composite fibers. The mechanical properties of the composites were significantly enhanced by the addition of the MWNTs. The PLGA/MWNTs/2.0 % wool keratin composite presented the best values of ultimate strength, elongation at break, and Young’s modulus. All of the PLGA/MWNTs/wool keratin composites showed high thermal and thermooxidative stabilities. After mineralization, apatite crystals were deposited on the PLGA/MWNTs/wool keratin membranes, suggesting that the composites possess high bioactivity. Thus, these new ternary PLGA/MWNTs/wool keratin membranes show great potential to meet the demand for GBR membranes.
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影响因子：
9.9
作者：
Xiao Yang;Hui Zhang;Xiaoliang Yuan;Shuxun Cui
通讯作者：
Xiao Yang;Hui Zhang;Xiaoliang Yuan;Shuxun Cui
DOI：
10.1007/s003920170048
发表时间：
2001
期刊：
Zeitschrift für Kardiologie
影响因子：
--
作者：
T. Kokubo;H.‐M. Kim;M. Kawashita;T. Nakamura
通讯作者：
T. Kokubo;H.‐M. Kim;M. Kawashita;T. Nakamura
影响因子：
14
作者：
T. Tanabe;Naoya Okitsu;A. Tachibana;K. Yamauchi
通讯作者：
T. Tanabe;Naoya Okitsu;A. Tachibana;K. Yamauchi
影响因子：
9.5
作者：
Ki, Chang Seok;Gang, Eun Hee;Park, Young Hwan
通讯作者：
Park, Young Hwan
影响因子：
14
作者：
Varma, HK;Yokogawa, Y;Kameyama, T
通讯作者：
Kameyama, T