Chemical warfare between fungus-growing ants and their pathogens.
Chemical warfare between fungus-growing ants and their pathogens.
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DOI：
10.1016/j.cbpa.2020.08.001
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发表时间：
2020-12
影响因子：
7.8
通讯作者：
Wilkinson B
中科院分区：
文献类型：
--
作者：
Batey SFD;Greco C;Hutchings MI;Wilkinson B
真菌生长的蚂蚁不断受到真菌病原体的威胁，例如专门的真菌寄生虫Escovopsis，它使用物理和化学攻击策略来捕食蚂蚁的真菌花园。为了防御，一些物种在其外骨骼上组装了保护性微生物群，其中含有产生抗菌素的放线菌。在这种互利和对抗的相互作用网络的基础上，是一系列的化学信号。Escovopsis weberi产生影响蚂蚁行为的剪切素term-吲哚生物碱，二酮哌嗪以对抗防御细菌，以及其他抑制真菌品种的小分子。假诺卡氏菌和链霉菌互惠细菌产生缩肽和多烯大环内酯抗真菌活性对Escovopsis spp。蚁巢代谢组由于防御细菌之间的竞争而进一步复杂化，这些防御细菌产生对甚至密切相关的物种具有活性的抗菌剂。专门的真菌病原体攻击真菌蚂蚁的巢穴。蚂蚁与防御性放线菌形成互惠关系。专门的代谢物支持这些互利和拮抗的相互作用。
Fungus-growing attine ants are under constant threat from fungal pathogens such as the specialized mycoparasite Escovopsis, which uses combined physical and chemical attack strategies to prey on the fungal gardens of the ants. In defence, some species assemble protective microbiomes on their exoskeletons that contain antimicrobial-producing Actinobacteria. Underlying this network of mutualistic and antagonistic interactions are an array of chemical signals. Escovopsis weberi produces the shearinine terpene-indole alkaloids, which affect ant behaviour, diketopiperazines to combat defensive bacteria, and other small molecules that inhibit the fungal cultivar. Pseudonocardia and Streptomyces mutualist bacteria produce depsipeptide and polyene macrolide antifungals active against Escovopsis spp. The ant nest metabolome is further complicated by competition between defensive bacteria, which produce antibacterials active against even closely related species. Specialist fungal pathogens attack the nests of fungus-growing ants. Ants form mutualistic relationships with defensive actinomycete bacteria. Specialised metabolites underpin these mutualistic and antagonistic interactions.
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影响因子：
2.7
作者：
Currie, CR
通讯作者：
Currie, CR
影响因子：
16.6
作者：
Heine D;Holmes NA;Worsley SF;Santos ACA;Innocent TM;Scherlach K;Patrick EH;Yu DW;Murrell JC;Vieria PC;Boomsma JJ;Hertweck C;Hutchings MI;Wilkinson B
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
4.3
作者：
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