Mindful Positive Emotion Regulation as a Treatment for Addiction: From Hedonic Pleasure to Self-Transcendent Meaning.
Mindful Positive Emotion Regulation as a Treatment for Addiction: From Hedonic Pleasure to Self-Transcendent Meaning.
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DOI：
10.1016/j.cobeha.2021.03.019
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发表时间：
2021-06
影响因子：
5
通讯作者：
Garland EL
中科院分区：
文献类型：
--
作者：
Garland EL
从理论上讲，慢性药物使用会诱导皮质纹状体神经可塑性，从而驱动一个适应过程，其特征是对药物相关线索的敏感性增加，对自然奖励的敏感性降低，从而导致快感缺乏和缺乏积极影响。因此，积极情绪调节是成瘾治疗的关键机制目标。本文提供了一个概念模型，详细说明了正念如何协同一系列积极的情感机制来减少成瘾行为，从享受自然奖励带来的享乐快乐，到自我产生的内感受性奖励反应，最终培养自我超越的意义。这些治疗过程可能会将奖励处理从对药物相关奖励的高估重新调整为对自然奖励的评估，并且假设“重置”了支持成瘾的默认模式网络功能障碍。
Chronic drug use is theorized to induce cortico-striatal neuroplasticity, driving an allostatic process marked by increased sensitivity to drug-related cues and decreased sensitivity to natural rewards that results in anhedonia and a dearth of positive affect. As such, positive emotion regulation represents a key mechanistic target for addictions treatment. This paper provides a conceptual model detailing how mindfulness may synergize a range of positive affective mechanisms to reduce addictive behavior, from savoring the hedonic pleasure derived from natural rewards, to self-generating interoceptive reward responses, and ultimately to cultivating self-transcendent meaning. These therapeutic processes may restructure reward processing from over-valuation of drug-related rewards back to valuation of natural rewards, and hypothetically, “reset” the default mode network dysfunction that undergirds addiction.
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DOI：
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发表时间：
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影响因子：
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