Prevalence of major cardiovascular risk factors and cardiovascular diseases among Hispanic/Latino individuals of diverse backgrounds in the United States.
Prevalence of major cardiovascular risk factors and cardiovascular diseases among Hispanic/Latino individuals of diverse backgrounds in the United States.
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DOI：
10.1001/jama.2012.14517
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发表时间：
2012-11-07
影响因子：
120.7
通讯作者：
Stamler, Jeremiah
中科院分区：
文献类型：
--
作者：
Daviglus, Martha L.;Talavera, Gregory A.;Aviles-Santa, M. Larissa;Allison, Matthew;Cai, Jianwen;Criqui, Michael H.;Gellman, Marc;Giachello, Aida L.;Gouskova, Natalia;Kaplan, Robert C.;LaVange, Lisa;Penedo, Frank;Perreira, Krista;Pirzada, Amber;Schneiderman, Neil;Wassertheil-Smoller, Sylvia;Sorlie, Paul D.;Stamler, Jeremiah
主要心血管疾病（CVD）是美国西班牙裔和拉丁裔个体死亡的主要原因。全面的数据是有限的，关于心血管疾病的危险因素在这一人群中的患病率和这些特征的社会经济地位（SES）和文化适应的关系。描述不同背景的美国西班牙裔/拉丁裔个体中主要CVD风险因素和CVD（冠心病[CHD]和卒中）的患病率，检查SES和文化适应与CVD风险特征和CVD的关系，并评估CVD风险因素与CVD的横断面相关性。多中心、前瞻性、基于人群的西班牙裔社区健康研究/拉丁美洲人研究，包括年龄在18至74岁之间的古巴人（n =2201）、多米尼加人（n = 1400）、墨西哥人（n=6232）、波多黎各人（n=2590）、中美洲人（n=1634）和南美洲背景（n = 1022）。分析涉及2008年3月至2011年6月期间入组的完整数据的15079名参与者。使用高胆固醇血症、高血压、肥胖、糖尿病和吸烟的国家指南定义的不良CVD风险因素。冠心病和中风的患病率从自我报告的数据中确定。CVD危险因素的标准化患病率因西班牙裔/拉丁裔背景而异;波多黎各参与者中肥胖和当前吸烟率最高（男性，40.9%和34.7%;女性，51.4%和31.7%）;高胆固醇血症患病率在中美洲男性（54.9%）和波多黎各女性（41.0%）中最高。大部分参与者（80%的男性，71%的女性）至少有一个风险因素。年龄和性别调整后的3个或更多风险因素的患病率在波多黎各参与者中最高（25.0%），教育程度较低的参与者（16.1%），美国出生的参与者（18.5%），在美国生活10年或更长时间的参与者（15.7%）和那些喜欢英语的参与者（17.9%）中显着更高（P<.001）。总体而言，自我报告的CHD和卒中患病率较低（男性分别为4.2%和2.0%;女性分别为2.4%和1.2%）。在多变量校正模型中，高血压和吸烟与男女CHD直接相关，女性高胆固醇血症和肥胖以及男性糖尿病也是如此（比值比[OR]，1.5-2.2）。对于中风，男女性高血压、男性糖尿病和女性吸烟均与中风呈正相关（OR，1.7-2.6）。在不同背景的美国西班牙裔/拉丁裔成年人中，相当大比例的男性和女性有不良的主要风险因素;在波多黎各背景、SES较低和文化适应水平较高的参与者中，不良心血管疾病风险特征的患病率较高。
Major cardiovascular diseases (CVDs) are leading causes of mortality among US Hispanic and Latino individuals. Comprehensive data are limited regarding the prevalence of CVD risk factors in this population and relations of these traits to socioeconomic status (SES) and acculturation. To describe prevalence of major CVD risk factors and CVD (coronary heart disease [CHD] and stroke) among US Hispanic/Latino individuals of different backgrounds, examine relationships of SES and acculturation with CVD risk profiles and CVD, and assess cross-sectional associations of CVD risk factors with CVD. Multicenter, prospective, population-based Hispanic Community Health Study/Study of Latinos including individuals of Cuban (n =2201), Dominican (n = 1400), Mexican (n=6232), Puerto Rican (n=2590), Central American (n=1634), and South American backgrounds (n = 1022) aged 18 to 74 years. Analyses involved 15 079 participants with complete data enrolled between March 2008 and June 2011. Adverse CVD risk factors defined using national guidelines for hypercholesterolemia, hypertension, obesity, diabetes, and smoking. Prevalence of CHD and stroke were ascertained from self-reported data. Age-standardized prevalence of CVD risk factors varied by Hispanic/Latino background; obesity and current smoking rates were highest among Puerto Rican participants (for men, 40.9% and 34.7%; for women, 51.4% and 31.7%, respectively); hypercholesterolemia prevalence was highest among Central American men (54.9%) and Puerto Rican women (41.0%). Large proportions of participants (80% of men, 71% of women) had at least 1 risk factor. Age- and sex-adjusted prevalence of 3 or more risk factors was highest in Puerto Rican participants (25.0%) and significantly higher (P<.001) among participants with less education (16.1%), those who were US-born (18.5%), those who had lived in the United States 10 years or longer (15.7%), and those who preferred English (17.9%). Overall, self-reported CHD and stroke prevalence were low (4.2% and 2.0% in men; 2.4% and 1.2% in women, respectively). In multivariate-adjusted models, hypertension and smoking were directly associated with CHD in both sexes as were hypercholesterolemia and obesity in women and diabetes in men (odds ratios [ORs], 1.5–2.2). For stroke, associations were positive with hypertension in both sexes, diabetes in men, and smoking in women (ORs, 1.7–2.6). Among US Hispanic/Latino adults of diverse backgrounds, a sizeable proportion of men and women had adverse major risk factors; prevalence of adverse CVD risk profiles was higher among participants with Puerto Rican background, lower SES, and higher levels of acculturation.
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影响因子：
120.7
作者：
Flegal, Katherine M.;Carroll, Margaret D.;Curtin, Lester R.
通讯作者：
Curtin, Lester R.
影响因子：
37.8
作者：
Roger VL;Go AS;Lloyd-Jones DM;Benjamin EJ;Berry JD;Borden WB;Bravata DM;Dai S;Ford ES;Fox CS;Fullerton HJ;Gillespie C;Hailpern SM;Heit JA;Howard VJ;Kissela BM;Kittner SJ;Lackland DT;Lichtman JH;Lisabeth LD;Makuc DM;Marcus GM;Marelli A;Matchar DB;Moy CS;Mozaffarian D;Mussolino ME;Nichol G;Paynter NP;Soliman EZ;Sorlie PD;Sotoodehnia N;Turan TN;Virani SS;Wong ND;Woo D;Turner MB;American Heart Association Statistics Committee and Stroke Statistics Subcommittee
通讯作者：
American Heart Association Statistics Committee and Stroke Statistics Subcommittee
影响因子：
5.6
作者：
Lavange, Lisa M.;Kalsbeek, William D.;Sorlie, Paul D.;Aviles-Santa, Larissa M.;Kaplan, Robert C.;Barnhart, Janice;Liu, Kiang;Giachello, Aida;Lee, David J.;Ryan, John;Criqui, Michael H.;Elder, John P.
通讯作者：
Elder, John P.
影响因子：
5
作者：
Allison, Matthew A.;Budoff, Matthew J.;Criqui, Michael H.
通讯作者：
Criqui, Michael H.
影响因子：
5
作者：
MARMOT, MG;SYME, SL
通讯作者：
SYME, SL