Long-term exposure to fine particulate matter and hospitalization in COVID-19 patients.
Long-term exposure to fine particulate matter and hospitalization in COVID-19 patients.
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COVID-19患者长期暴露于细颗粒物和住院治疗。
DOI:
10.1016/j.rmed.2021.106313
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发表时间:
2021-03
影响因子:
4.3
通讯作者:
Pinney SM
中科院分区:
文献类型:
--
作者:
Mendy A;Wu X;Keller JL;Fassler CS;Apewokin S;Mersha TB;Xie C;Pinney SM
Ecological evidence suggests that exposure to air pollution affects coronavirus disease 2019 (COVID-19) outcomes. However, no individual-level study has confirmed the association to date. We identified COVID-19 patients diagnosed at the University of Cincinnati hospitals and clinics and estimated particulate matter ≤2.5 μm (PM2.5) exposure over a 10-year period (2008–2017) at their residential zip codes. We used logistic regression to evaluate the association between PM2.5 exposure and hospitalizations for COVID-19, adjusting for socioeconomic characteristics and comorbidities. Among the 1128 patients included in our study, the mean (standard deviation) PM2.5 was 11.34 (0.70) μg/m3 for the 10-year average exposure and 13.83 (1.03) μg/m3 for the 10-year maximal exposures. The association between long-term PM2.5 exposure and hospitalization for COVID-19 was contingent upon having pre-existing asthma or chronic obstructive pulmonary (COPD) (Pinteraction = 0.030 for average PM2.5 and Pinteraction = 0.001 for maximal PM2.5). In COVID-19 patients with asthma or COPD, the odds of hospitalization were 62% higher with 1 μg/m3 increment in 10-year average PM2.5 (odds ratio [OR]: 1.62, 95% confidence interval [CI]: 1.00–2.64) and 65% higher with 1 μg/m3 increase in 10-year maximal PM2.5 levels (OR: 1.65, 95% CI: 1.16–2.35). However, among COVID-19 patients without asthma or COPD, PM2.5 exposure was not associated with higher hospitalizations (OR: 0.84, 95% CI: 0.65–1.09 for average PM2.5 and OR: 0.78, 95% CI: 0.65–0.95 for maximal PM2.5). Long-term exposure to PM2.5 is associated with higher odds of hospitalization in COVID-19 patients with pre-existing asthma or COPD.
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影响因子:
13.6
作者:
Wu X;Nethery RC;Sabath MB;Braun D;Dominici F
通讯作者:
Dominici F
DOI:
10.1186/1476-069x-13-2
发表时间:
2014-01-13
期刊:
Environmental health : a global access science source
影响因子:
--
作者:
Kioumourtzoglou MA;Spiegelman D;Szpiro AA;Sheppard L;Kaufman JD;Yanosky JD;Williams R;Laden F;Hong B;Suh H
通讯作者:
Suh H
影响因子:
8.3
作者:
Gasana, Janvier;Dillikar, Deepa;Vieira, Edgar Ramos
通讯作者:
Vieira, Edgar Ramos
影响因子:
11.4
作者:
van Donkelaar, Aaron;Martin, Randall V.;Burnett, Richard T.
通讯作者:
Burnett, Richard T.
DOI:
10.1164/rccm.201809-1733oc
发表时间:
2019-09-15
影响因子:
24.7
作者:
Mendy, Angelico;Wilkerson, Jesse;Thorne, Peter S.
通讯作者:
Thorne, Peter S.