Femoral head collapse rate among Japanese patients with pre-collapse osteonecrosis of the femoral head.

Femoral head collapse rate among Japanese patients with pre-collapse osteonecrosis of the femoral head.
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日本股骨头塌陷前骨坏死患者的股骨头塌陷率。

DOI:
10.1177/03000605211023336
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发表时间:
2021-06
期刊:
The Journal of international medical research
影响因子:
--
通讯作者:
Akiyama H
Akiyama H
中科院分区:
其他
文献类型:
--
作者:
Asada R;Abe H;Hamada H;Fujimoto Y;Choe H;Takahashi D;Ueda S;Kuroda Y;Miyagawa T;Yamada K;Tanaka T;Ito J;Morita S;Takagi M;Tetsunaga T;Kaneuji A;Inaba Y;Tanaka S;Matsuda S;Sugano N;Akiyama H

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在这项研究中,我们的目的是阐明从诊断到股骨头塌陷的时间和塌陷率之间的关系,在股骨头塌陷前骨坏死(ONFH)患者。在这项回顾性、观察性、多中心研究中,我们分析了268例诊断为ONFH的患者,并使用日本调查委员会分类法对其进行分类。主要终点是每种ONFH从诊断到股骨头塌陷的时间。参与者12、24和36个月的崩溃率分别为A型0%、0%和0%; B型0%、2.0%和10.8%; C-1型分别为25.5%、40.8%和48.5%; C-2型ONFH分别为57.4%、70.3%和76.7%。使用Kaplan-Meier生存曲线比较单侧和双侧ONFH显示出相似的塌陷率。A型ONFH的塌陷率最低,其次是B、C-1和C-2型。此外,在塌陷率和承重表面骨坏死病变的位置之间观察到直接相关性。
In this study, we aimed to elucidate the relationship between the duration from diagnosis to femoral head collapse and the collapse rate among patients with pre-collapse osteonecrosis of the femoral head (ONFH). In this retrospective, observational, multicenter study, we analyzed 268 patients diagnosed with ONFH and classified them using the Japanese Investigation Committee classification. The primary endpoint was duration from the time of diagnosis to femoral head collapse for each type of ONFH. The 12-, 24-, and 36-month collapse rates among participants were 0%, 0%, and 0% for type A, respectively; 0%, 2.0%, and 10.8% for type B, respectively; 25.5%, 40.8%, and 48.5% for type C-1, respectively; and 57.4%, 70.3%, and 76.7% for type C-2 ONFH, respectively. A comparison of unilateral and bilateral ONFH, using Kaplan–Meier survival curves demonstrated similar collapse rates. The lowest collapse rate was observed for ONFH type A, followed by types B, C-1, and C-2. Additionally, a direct association was observed between the collapse rate and location of the osteonecrotic lesion on the weight-bearing surface.
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