Biobehavioral profiles of arousal and social motivation in autism spectrum disorders.
Biobehavioral profiles of arousal and social motivation in autism spectrum disorders.
复制标题
DOI：
10.1111/jcpp.12184
复制
发表时间：
2014-08
期刊：
影响因子：
--
通讯作者：
Edgerton D
中科院分区：
文献类型：
--
作者：
Corbett BA;Swain DM;Newsom C;Wang L;Song Y;Edgerton D
患有自闭症谱系障碍(ASD)的儿童在与同伴的社会交流和互动中受到损害，这可能反映了社会动机的减弱。许多患有自闭症的儿童在与其他儿童玩耍时表现出更大的压力。本研究调查了自闭症儿童在游戏过程中的社交和压力状况。我们在一个自然的操场环境中使用了同伴互动范式，有66名8至12岁的未服用药物的青春期前儿童(38名患有自闭症，28名具有典型发育(TD))。在20分钟的操场互动前后收集唾液皮质醇，互动分为免费和请求游戏的时间段，由邦联儿童促成。统计分析包括Wilcoxon秩和检验、混合效应模型和Spearman相关性，以分别评估组内社交和压力功能的差异，确定压力响应者，并探索变量之间的关联。在主动自由游戏期间，两组儿童之间没有差异；然而，在邦联成员请求的游戏期间，出现了显著的差异，患有自闭症的儿童比TD组参与更少的言语互动和更多的自我游戏。在生理唤醒方面，自闭症儿童作为一个群体，在社交游戏中表现出相对较高的皮质醇；然而，有广泛的反应范围。此外，皮质醇水平最高的人参与的社交活动较少。患有自闭症的儿童的社会互动可以通过同伴请求来促进；然而，这可能伴随着更多的压力。皮质醇水平最高的自闭症儿童表现出的社交动机较少；然而，尚不清楚这是否反映了一种潜在的状态，即对社交活动的高度唤醒或反应增强，或者两者兼而有之。
Children with autism spectrum disorder (ASD) are impaired in social communication and interaction with peers, which may reflect diminished social motivation. Many children with ASD show enhanced stress when playing with other children. This study investigated social and stress profiles of children with ASD during play. We utilized a peer interaction paradigm in a natural playground setting with 66 un-medicated, pre-pubertal, children 8 to 12 years (38 with ASD, 28 with typical development (TD)). Salivary cortisol was collected before and after a 20-minute playground interaction that was divided into periods of free and solicited play facilitated by a confederate child. Statistical analyses included Wilcoxon rank-sum tests, mixed effects models and Spearman correlations to assess the between-group differences in social and stress functioning, identify stress responders, and explore associations between variables, respectively. There were no differences between the groups during unsolicited free play; however, during solicited play by the confederate, significant differences emerged such that children with ASD engaged in fewer verbal interactions and more self-play than the TD group. Regarding physiological arousal, children with ASD as a group showed relatively higher cortisol in response to social play; however, there was a broad range of responses. Moreover, those with the highest cortisol levels engaged in less social communication. The social interaction of children with ASD can be facilitated by peer solicitation; however, it may be accompanied by increased stress. The children with ASD that have the highest level of cortisol show less social motivation; yet, it is unclear if it reflects an underlying state of heightened arousal or enhanced reactivity to social engagement, or both.
登录
查看更多内容
DOI：
10.1111/j.1469-7610.2011.02493.x
发表时间：
2012-04
期刊：
Journal of child psychology and psychiatry, and allied disciplines
影响因子：
--
作者：
Kasari C;Rotheram-Fuller E;Locke J;Gulsrud A
通讯作者：
Gulsrud A
影响因子：
4.6
作者：
BROOKSGUNN, J;WARREN, MP;GARGIULO, J
通讯作者：
GARGIULO, J
DOI：
10.1097/chi.0b013e31812f7d8d
发表时间：
2007-10-01
影响因子：
13.3
作者：
Chandler, Susie;Charman, Tony;Pickles, Andrew
通讯作者：
Pickles, Andrew
影响因子：
3.9
作者：
Corbett, Blythe A.;Gunther, Joan R.;Rios, Taylor
通讯作者：
Rios, Taylor
影响因子：
3.9
作者：
Daluwatte C;Miles JH;Christ SE;Beversdorf DQ;Takahashi TN;Yao G
通讯作者：
Yao G