The household distribution of trachoma in a Tanzanian village: an application of GIS to the study of trachoma.

The household distribution of trachoma in a Tanzanian village: an application of GIS to the study of trachoma.
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DOI:
10.1016/j.trstmh.2004.06.010
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发表时间:
2005-03
影响因子:
2.2
通讯作者:
Mabey DC
Mabey DC
中科院分区:
医学4区
文献类型:
--
作者:
Polack SR;Solomon AW;Alexander ND;Massae PA;Safari S;Shao JF;Foster A;Mabey DC

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活动性沙眼分布在一个流行的村庄,约1000人(Kahe Mpya,坦桑尼亚)进行了空间映射和分析相关的危险因素和证据的集群。研究证明了距水源的距离与活动性疾病之间存在关联,尽管在考虑到同一家庭中病例之间缺乏独立性后,这种关联有所减少。活动性沙眼在家庭内的显著聚集性被证明,增加了对家庭内传播的假设重要性的支持。沙眼的空间分布进行了分析,使用空间扫描统计,并发现活动性沙眼病例的聚集性证据。了解疾病的分布情况对了解传播的动态以及因此采取适当的控制活动具有重要意义。所展示的空间聚集表明,在这种情况下,家庭间以及家庭内感染传播可能很常见。活动性沙眼和地理信息系统测量的距离水之间的关联可能是相关的规划控制措施。
The distribution of active trachoma in an endemic village of approximately 1000 people (Kahe Mpya, Tanzania) was mapped spatially and analysed for associated risk factors and evidence of clustering. An association between distance to water source and active disease was demonstrated, although this was reduced after accounting for the lack of independence between cases in the same household. Significant clustering of active trachoma within households was demonstrated, adding support to the hypothesised importance of intra-familial transmission. The spatial distribution of trachoma was analysed using the spatial scan statistic, and evidence of clustering of active trachoma cases detected. Understanding the distribution of the disease has implications for understanding the dynamics of transmission and therefore appropriate control activities. The demonstrated spatial clustering suggests inter-familial as well as intra-familial transmission of infection may be common in this setting. The association between active trachoma and GIS-measured distance to water may be relevant for planning control measures.
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