Electrochemical Sensors for Detection of Markers on Tumor Cells.
Electrochemical Sensors for Detection of Markers on Tumor Cells.
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用于检测肿瘤细胞标记物的电化学传感器
DOI：
10.3390/ijms22158184
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发表时间：
2021-07-30
影响因子：
5.6
通讯作者：
Zhang Z
中科院分区：
文献类型：
--
作者：
Zhou H;Du X;Zhang Z
近年来，癌症发病率和死亡率的不断上升促使人们开发准确、快速的早期诊断方法来成功治愈癌症；然而，用于检测肿瘤细胞的常规方法，包括组织病理学和免疫学方法，除了需要有经验的人员外，往往涉及复杂的操作过程、高昂的分析成本和高的假阳性率。随着传感技术的迅速兴起，电化学细胞传感器以其灵敏度高、设备简单、成本低等优点在肿瘤细胞检测领域引起了广泛的关注。这些细胞传感器不仅能够区分肿瘤细胞和正常细胞，而且还可以对肿瘤细胞进行靶向蛋白质检测。本文综述了近五年来报道的用于肿瘤细胞检测的各种电化学细胞传感器的研究成果，包括细胞传感器的结构、检测范围和检测下限。对电化学细胞传感器的发展趋势和前景进行了讨论。
In recent years, the increasing incidence and mortality of cancer have inspired the development of accurate and rapid early diagnosis methods in order to successfully cure cancer; however, conventional methods used for detecting tumor cells, including histopathological and immunological methods, often involve complex operation processes, high analytical costs, and high false positive rates, in addition to requiring experienced personnel. With the rapid emergence of sensing techniques, electrochemical cytosensors have attracted wide attention in the field of tumor cell detection because of their advantages, such as their high sensitivity, simple equipment, and low cost. These cytosensors are not only able to differentiate tumor cells from normal cells, but can also allow targeted protein detection of tumor cells. In this review, the research achievements of various electrochemical cytosensors for tumor cell detection reported in the past five years are reviewed, including the structures, detection ranges, and detection limits of the cytosensors. Certain trends and prospects related to the electrochemical cytosensors are also discussed.
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影响因子：
64.5
作者：
Cheng, Y;Zak, O;Walz, T
通讯作者：
Walz, T
影响因子：
6.2
作者：
Chowdhury, Ankan Dutta;Ganganboina, Akhilesh Babu;Doong, Ruey-an
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Doong, Ruey-an
DOI：
10.1016/j.msec.2020.111549
发表时间：
2021-02-01
影响因子：
7.9
作者：
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影响因子：
3.8
作者：
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影响因子：
3.9
作者：
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通讯作者：
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