Fluorescent probes for sensing and imaging biological hydrogen sulfide.
Fluorescent probes for sensing and imaging biological hydrogen sulfide.
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DOI:
10.1016/j.cbpa.2012.07.014
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发表时间:
2012-12
影响因子:
7.8
通讯作者:
Chang, Christopher J.
中科院分区:
文献类型:
--
作者:
Lin, Vivian S.;Chang, Christopher J.
Hydrogen sulfide (H2S) has long been recognized as a toxic molecule in biological systems. However, emerging studies now link controlled fluxes of this reactive sulfur species to cellular regulation and signaling events akin to other small molecule messengers, such as nitric oxide, hydrogen peroxide, and carbon monoxide. Progress in the development of fluorescent small-molecule indicators with high selectivity for hydrogen sulfide offers a promising approach for studying its production, trafficking, and downstream physiological and/or pathological effects.
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