Review: in vitro microvessel models.
Review: in vitro microvessel models.
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DOI:
10.1039/c5lc00832h
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发表时间:
2015-11-21
期刊:
影响因子:
6.1
通讯作者:
Searson, Peter C.
中科院分区:
文献类型:
--
作者:
Bogorad, Max I.;DeStefano, Jackson;Karlsson, Johan;Wong, Andrew D.;Gerecht, Sharon;Searson, Peter C.
A wide range of perfusable microvessel models have been developed, exploiting advances in microfabrication, microfluidics, biomaterials, stem cell technology, and tissue engineering. These models vary in complexity and physiological relevance, but provide a diverse tool kit for the study of vascular phenomena and methods to vascularize artificial organs. Here we review the state-of-the-art in perfusable microvessel models, summarizing the different fabrication methods and highlighting advantages and limitations.
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