Relative food preference and hedonic judgments in schizophrenia.
Relative food preference and hedonic judgments in schizophrenia.
复制标题
DOI：
10.1016/j.psychres.2008.07.026
复制
发表时间：
2010-01-30
影响因子：
11.3
通讯作者：
Park, Sohee
中科院分区：
文献类型：
--
作者：
Folley, Bradley S.;Park, Sohee
有充分证据表明，精神分裂症患者的奖励评估相关的神经网络受到破坏。同样的系统也参与编码健康个体的食物激励价值，但是迄今为止还没有研究检查精神分裂症患者的快感缺乏及其与食物的关系。研究人员对精神分裂症患者和健康对照者的相对偏好和享乐食物评级进行了检查。在相对偏好任务中，受试者观看食物照片并选择他们最喜欢的食物。享乐评级是通过询问受试者对食物刺激的喜爱程度（1-5 级）来获得的。在相对偏好任务中，两组之间没有总体反应时间差异，但与对照组相比，精神分裂症患者对食物的享乐评级表现出细微的差异。与对照组相比，精神分裂症患者对食物给予更多积极的享乐评价，而较少的积极评价与快感缺失增加有关，特别是与性兴趣丧失有关。这些结果表明，虽然相对偏好判断可能完好无损，但精神分裂症患者对食物的享乐价值可能会发生改变，并且它们可能与更基本的植物系统的功能障碍有关。这些发现可能有助于根据记录与精神分裂症已知功能失调系统相关的特征，阐明人类受试者的食物偏好和判断的更一般模型。
There is a well-documented disruption of the neural network associated with reward evaluation in schizophrenia. This same system is involved in coding the incentive value of food in healthy individuals, however no study to date has examined anhedonia and its relation to food in schizophrenia. Relative preference and hedonic food ratings were examined in schizophrenia patients and healthy controls. In the relative preference task, subjects viewed photographs of food items and selected the one that they most preferred. Hedonic ratings were obtained by asking subjects how much they liked the food stimulus on a scale of 1–5. There were no overall response time differences between the two groups in the relative preference task but schizophrenic patients showed subtle differences in their hedonic ratings of foods compared with control subjects. Schizophrenic patients gave more positive hedonic ratings for food than controls and the use of fewer positive ratings was associated with increased anhedonia, particularly with loss of sexual interest. These results suggest that while making relative preference judgments may be intact, hedonic values attached to food may be altered in schizophrenia, and they may be related to dysfunction in more basic vegetative systems. These findings may help to elucidate a more general model of food preference and judgment in human subjects based on documenting characteristics associated with a known dysfunctional system in schizophrenia.
登录
查看更多内容
影响因子：
4.6
作者：
BERENBAUM, H;OLTMANNS, TF
通讯作者：
OLTMANNS, TF
影响因子：
1.9
作者：
LaBar, KS;Gitelman, DR;Mesulam, MM
通讯作者：
Mesulam, MM
影响因子：
56.9
作者：
BUTTER, CM;MCDONALD, JA;SNYDER, DR
通讯作者：
SNYDER, DR
影响因子：
2.9
作者：
Kim, JS;Choi, S
通讯作者：
Choi, S
影响因子：
2.9
作者：
Finlayson, Graham;King, Neil;Blundell, John E.
通讯作者：
Blundell, John E.