Higher-order cognitive training effects on processing speed-related neural activity: a randomized trial.
Higher-order cognitive training effects on processing speed-related neural activity: a randomized trial.
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DOI：
10.1016/j.neurobiolaging.2017.10.003
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发表时间：
2018-03
影响因子：
4.2
通讯作者：
Chapman SB
中科院分区：
文献类型：
--
作者：
Motes MA;Yezhuvath US;Aslan S;Spence JS;Rypma B;Chapman SB
高阶认知训练已被证明可以提高老年人的表现，但提高表现的神经机制尚未完全消除歧义。这项随机试验检查了接受认知训练（CT，N = 12）的老年参与者（57-71岁）的处理速度和处理速度相关神经活动的变化，与候补名单（WLC，N = 15）或运动训练活跃（AC，N = 14）对照相比。认知训练在 12 周内教授策略注意力、综合推理和创新等认知控制功能。所有三个小组在三个阶段（基线、训练中期和训练后）都完成了功能磁共振成像处理速度任务。尽管所有组在整个疗程中都表现出更快的反应时间 (RT)，但 CT 组在左前额皮质 (PFC) 内的 RT 和 BOLD 信号变化之间的关联显示出显着增加，而 WLC 和 AC 组在整个疗程中显示出显着减少。因此，认知训练导致与处理速度相关的神经活动发生变化，其中更快的处理速度与减少的 PFC 激活相关，符合先前确定的神经效率概况。 ClinicalTrials.gov，NCT# 00977418
Higher-order cognitive training has shown to enhance performance in older adults, but the neural mechanisms underlying performance enhancement have yet to be fully disambiguated. This randomized trial examined changes in processing speed and processing speed-related neural activity in older participants (57–71 years of age) who underwent cognitive training (CT, N=12) compared to wait-listed (WLC, N=15) or exercise-training active (AC, N=14) controls. The cognitive training taught cognitive control functions of strategic attention, integrative reasoning, and innovation over 12 weeks. All three groups worked through an fMRI processing speed task during three sessions (baseline, mid-training, and post-training). Although all groups showed faster reaction times (RT) across sessions, the CT group showed a significant increase and the WLC and AC groups showed significant decreases across sessions in the association between RT and BOLD signal-change within left prefrontal cortex (PFC). Thus, cognitive training led to a change in processing speed-related neural activity where faster processing speed was associated with reduced PFC activation, fitting previously identified neural efficiency profiles. ClinicalTrials.gov, NCT# 00977418
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DOI：
10.1093/cercor/bhp284
发表时间：
2010-09
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Biswal BB;Eldreth DA;Motes MA;Rypma B
通讯作者：
Rypma B
影响因子：
3.7
作者：
Basak, Chandramallika;Boot, Walter R.;Voss, Michelle W.;Kramer, Arthur F.
通讯作者：
Kramer, Arthur F.
影响因子：
3.7
作者：
Baniqued, Pauline L.;Allen, Courtney M.;Kramer, Arthur F.
通讯作者：
Kramer, Arthur F.
影响因子：
5.7
作者：
Cohen, MS
通讯作者：
Cohen, MS
影响因子：
3.7
作者：
Baltes, PB;Lindenberger, U
通讯作者：
Lindenberger, U