Future of the particle replication in nonwetting templates (PRINT) technology.

Future of the particle replication in nonwetting templates (PRINT) technology.
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DOI:
10.1002/anie.201209145
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发表时间:
2013-06-24
影响因子:
16.6
通讯作者:
DeSimone, Joseph M.
DeSimone, Joseph M.
中科院分区:
化学1区
文献类型:
--
作者:
Xu, Jing;Wong, Dominica H. C.;Byrne, James D.;Chen, Kai;Bowerman, Charles;DeSimone, Joseph M.

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非润湿模板中的颗粒复制(PRINT)是一种连续的、卷对卷的高分辨率成型技术,可以设计和合成精确定义的微颗粒和纳米颗粒。该技术采用了微电子工业的光刻技术,并将其与照相胶片工业的卷对卷工艺相结合,使研究人员能够对颗粒大小、形状、化学成分、载货量、模数和表面性能进行前所未有的控制。此外,PRINT是一个符合GMP (GMP =良好生产规范)的平台,适用于大规模的颗粒制造。在这里,我们描述了一些我们最近的工作,涉及打印技术在生物医学和材料科学中的应用。
Particle replication in nonwetting templates (PRINT) is a continuous, roll-to-roll, high-resolution molding technology which allows the design and synthesis of precisely defined micro- and nanoparticles. This technology adapts the lithographic techniques from the microelectronics industry and marries these with the roll-to-roll processes from the photographic film industry to enable researchers to have unprecedented control over particle size, shape, chemical composition, cargo, modulus, and surface properties. In addition, PRINT is a GMP-compliant (GMP = good manufacturing practice) platform amenable for particle fabrication on a large scale. Herein, we describe some of our most recent work involving the PRINT technology for application in the biomedical and material sciences.
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