A role for the cortex in sleep-wake regulation.
A role for the cortex in sleep-wake regulation.
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DOI:
10.1038/s41593-021-00894-6
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发表时间:
2021-09
影响因子:
25
通讯作者:
Vyazovskiy VV
中科院分区:
文献类型:
--
作者:
Krone LB;Yamagata T;Blanco-Duque C;Guillaumin MCC;Kahn MC;van der Vinne V;McKillop LE;Tam SKE;Peirson SN;Akerman CJ;Hoerder-Suabedissen A;Molnár Z;Vyazovskiy VV
Cortical and subcortical circuitry are thought to play distinct roles in the generation of sleep oscillations and global state control, respectively. Here we silenced a subset of neocortical layer 5 pyramidal and archicortical dentate gyrus granule cells in male mice by ablating SNAP25. This markedly increased wakefulness and reduced rebound of EEG slow-wave activity after sleep deprivation, suggesting a role for the cortex in both vigilance state control and sleep homeostasis.
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DOI:
10.1523/jneurosci.2513-17.2018
发表时间:
2018-04-18
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
McKillop LE;Fisher SP;Cui N;Peirson SN;Foster RG;Wafford KA;Vyazovskiy VV
通讯作者:
Vyazovskiy VV
影响因子:
3.7
作者:
Hoerder-Suabedissen, Anna;Korrell, Kim V.;Molnar, Zoltan
通讯作者:
Molnar, Zoltan
影响因子:
16.2
作者:
Lefort, Sandrine;Tomm, Christian;Petersen, Carl C. H.
通讯作者:
Petersen, Carl C. H.
影响因子:
25
作者:
Gent TC;Bandarabadi M;Herrera CG;Adamantidis AR
通讯作者:
Adamantidis AR
影响因子:
--
作者:
Brown LA;Hasan S;Foster RG;Peirson SN
通讯作者:
Peirson SN