Relation between sleep quality and quantity, quality of life, and risk of developing diabetes in healthy workers in Japan: the High-risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study.
Relation between sleep quality and quantity, quality of life, and risk of developing diabetes in healthy workers in Japan: the High-risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study.
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DOI：
10.1186/1471-2458-7-129
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发表时间：
2007-06-28
影响因子：
4.5
通讯作者：
HIPOP-OHP Research group
中科院分区：
文献类型：
--
作者：
Hayashino Y;Fukuhara S;Suzukamo Y;Okamura T;Tanaka T;Ueshima H;HIPOP-OHP Research group
睡眠对患糖尿病风险的影响尚未在亚洲人群中进行过研究。本研究的目的是在日本的一个前瞻性队列中调查自我报告的睡眠时间和睡眠质量对患糖尿病风险的影响。数据分析来自1999年至2004年在日本进行的职业健康促进研究（HIPOP-OHP）的高风险和人口战略参与者队列。采用考克斯比例风险模型评估睡眠时间或睡眠质量与糖尿病风险之间的关系。在6509名参与者（26.1%的女性，19-69岁）中，在中位4.2年的随访中，共报告了230例2型糖尿病病例。对于经常出现入睡困难的受试者，入睡困难频率中等的受试者的糖尿病多变量校正风险比为1.42（95%CI，1.05-1.91），频率高的受试者为1.61（95%CI，1.00-2.58），具有统计学显著的线性趋势。在维持睡眠困难或睡眠持续时间与糖尿病风险之间的关联中未观察到显著关联。在相对健康的亚洲工人中，即使在调整了大量可能的其他因素后，中等和高频率的入睡困难，而不是维持睡眠或睡眠持续时间的困难，与糖尿病的高风险相关。
The effect of sleep on the risk of developing diabetes has not been explored in an Asian population. The objective of this study is to investigate the effect of self-reported sleep duration and sleep quality on the risk of developing diabetes in a prospective cohort in Japan. Data were analyzed from the cohort of participants in a High-risk and Population Strategy for Occupational Health Promotion Study (HIPOP-OHP), conducted in Japan from the year 1999 until 2004. A Cox proportional hazard model was used to evaluate the association between sleep duration or sleep quality and the risk of diabetes. Of 6509 participants (26.1% of women, 19–69 years of age), a total of 230 type 2 diabetes cases were reported over a median 4.2 years of follow-up. For participants who often experienced difficulty in initiating sleep, the multivariate-adjusted hazard ratios for diabetes were 1.42 (95%CI, 1.05–1.91) in participants with a medium frequency of difficulty initiating sleep, and 1.61 (95%CI, 1.00–2.58) for those with a high frequency, with a statistically significant linear trend. Significant association was not observed in the association between difficulty of maintaining sleep or duration of sleep, and risk of diabetes. Medium and high frequencies of difficulty initiating sleep, but not difficulty in maintaining sleep or in sleep duration, are associated with higher risks of diabetes in relatively healthy Asian workers, even after adjusting for a large number of possible further factors.
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影响因子：
7.2
作者：
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通讯作者：
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通讯作者：
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