Hydroxyapatite grafted carbon nanotubes and graphene nanosheets: promising bone implant materials.
Hydroxyapatite grafted carbon nanotubes and graphene nanosheets: promising bone implant materials.
复制标题
DOI：
10.1016/j.saa.2014.04.004
复制
发表时间：
2014-11-11
影响因子：
4.4
通讯作者：
Oki, Aderemi
中科院分区：
文献类型：
--
作者：
Oyefusi, Adebola;Olanipekun, Opeyemi;Neelgund, Gururaj M.;Peterson, Deforest;Stone, Julia M.;Williams, Ebonee;Carson, Laura;Regisford, Gloria;Oki, Aderemi
在本研究中，羟基磷灰石（HA）被成功地接枝到羧基化的碳纳米管（CNTs）和石墨烯纳米片。采用FT-IR、TGA、SEM和X射线衍射等方法对HA接枝的碳纳米管和HA-石墨烯纳米片进行了表征。进一步使用HA接枝的碳纳米管和石墨烯纳米片（CNTs-HA和Gr-HA）来检测温度敏感的人胎儿成骨细胞系（hFOB 1.19）的增殖和分化率。骨钙素表达的总蛋白测定和蛋白质印迹分析被用作细胞增殖和分化的指标。结果表明，hFOB 1.19细胞在含有CNTs-HA和石墨烯-HA的处理培养基中增殖和分化良好。碳纳米管-羟基磷灰石和石墨烯-羟基磷灰石可能是有前途的纳米材料，用于骨组织工程的支架。
In the present study, hydroxyapatite (HA) was successfully grafted to carboxylated carbon nanotubes (CNTs) and graphene nanosheets. The HA grafted CNTs and HA-graphene nanosheets were characterized using FT-IR, TGA, SEM and X-ray diffraction. The HA grafted CNTs and graphene nanosheets (CNTs-HA and Gr-HA) were further used to examine the proliferation and differentiation rate of temperature-sensitive human fetal osteoblastic cell line (hFOB 1.19). Total protein assays and western blot analysis of osteocalcin expression were used as indicators of cell proliferation and differentiation. Results indicated that hFOB 1.19 cells proliferate and differentiate well in treatment media containing CNTs-HA and graphene-HA. Both CNTs-HA and graphene-HA could be promising nanomaterials for use as scaffolds in bone tissue engineering.
登录
查看更多内容
沉积在聚（乳酸）接枝碳纳米管上的PD纳米颗粒：在HECK C-C偶联反应中的合成，表征和应用。
影响因子：
5.5
作者：
Neelgund, Gururaj M.;Oki, Aderemi
通讯作者：
Oki, Aderemi
影响因子：
4.9
作者：
MacDonald, RA;Laurenzi, BF;Stegemann, JP
通讯作者：
Stegemann, JP
影响因子：
11.4
作者：
Jia, G;Wang, HF;Guo, XB
通讯作者：
Guo, XB
影响因子：
15
作者：
HUMMERS, WS;OFFEMAN, RE
通讯作者：
OFFEMAN, RE
影响因子：
--
作者：
Choi, Eun-Young;Han, Tae Hee;Kim, Sang Ouk
通讯作者：
Kim, Sang Ouk