Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screening.
Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screening.
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癌症光学成像的当前和未来临床应用：从术中手术指导到癌症筛查。
DOI：
10.1053/j.seminoncol.2010.11.008
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发表时间：
2011-02
影响因子：
4
通讯作者：
Yang L
中科院分区：
文献类型：
--
作者：
Hadjipanayis CG;Jiang H;Roberts DW;Yang L
光学成像是一种廉价、快速且灵敏的成像方法，用于在光学成像设备可到达的位置对人类癌症进行非侵入性检测。光用于探测活体癌症中的细胞和分子功能。光学仪器发展的最新进展使得检测在几厘米的组织深度产生的光信号成为可能。光学信号可以是捕获包括肿瘤在内的不同组织的异质性和生物状态的内源性对比，也可以是选择性累积在肿瘤中以在局部或全身递送后成像的外在光学对比。除了癌症筛查之外，光学成像现在还应用于临床和手术室，用于恶性肿瘤的定位和切除。
Optical imaging is an inexpensive, fast, and sensitive imaging approach for the non-invasive detection of human cancers in locations that are accessible by an optical imaging device. Light is used to probe cellular and molecular function in the context of cancer in the living body. Recent advances in the development of optical instrumentation make it possible to detect optical signals produced at a tissue depth of several centimeters. The optical signals can be endogenous contrasts that capture the heterogeneity and biological status of different tissues including tumors, or extrinsic optical contrasts that selectively accumulate in tumors to be imaged after local or systemic delivery. The use of optical imaging is now being applied in the clinic and operating room for the localization and resection of malignant tumors in addition to screening for cancer.
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影响因子：
120.7
作者：
Bluemke, DA;Gatsonis, CA;Schnall, MD
通讯作者：
Schnall, MD
影响因子：
39.2
作者：
Carney, PA;Miglioretti, DL;Ballard-Barbash, R
通讯作者：
Ballard-Barbash, R
影响因子：
10.6
作者：
Jiang, H;Xu, Y;Fajardo, L
通讯作者：
Fajardo, L
影响因子：
46.9
作者：
Becker, A;Hessenius, C;Grötzinger, C
通讯作者：
Grötzinger, C
影响因子：
3.8
作者：
Corlu, Alper;Choe, Regine;Yodh, Arjun G.
通讯作者：
Yodh, Arjun G.