The "epiTet" of Air Pollution: Epigenetic Regulation of Airway Inflammation by Tet1.
The "epiTet" of Air Pollution: Epigenetic Regulation of Airway Inflammation by Tet1.
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DOI：
10.1159/000530272
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发表时间：
2023
影响因子：
2.8
通讯作者：
中科院分区：
文献类型：
--
作者：
空气污染是对健康的重大环境风险，导致许多疾病。患有慢性呼吸道疾病的人和儿童特别容易受到有害的呼吸系统影响[1]。高达45%的美国人口，主要是贫困人口、城市人口和少数民族，居住在交通相关空气污染（TRAP）高暴露地区[3]。5（颗粒直径< 2.5 µm的颗粒物），一直与儿童哮喘急性发作和发病率、持续性肺功能变化、哮喘和其他肺部疾病的风险较高以及呼吸道感染后果（如COVID严重程度）恶化相关[4]。其他气态空气污染物，如氮氧化物、挥发性有机化合物和臭氧，也观察到类似的健康影响。尽管在过去十年中在减少暴露于空气污染物方面取得了进展，但TRAP和其他空气污染物来源（例如，由于气候变化导致的反复野火烟雾暴露）仍然对公众健康和环境构成重大风险。
Air pollution is a significant environmental risk to health, leading to many diseases. People with chronic respiratory diseases and children are especially vulnerable to detrimental respiratory effects [1]. Up to 45% of the US population, predominately poor, urban populations and racial minorities, resides in areas of high traffic-related air pollution (TRAP) exposure [3].Exposure to TRAP, including PM2. 5 (particulate matter with particles< 2.5 µm in diameter), has been consistently associated with childhood asthma exacerbations and incidence, persistent lung function changes, higher risk of asthma and other lung diseases, and worse respiratory infection outcomes such as COVID severity [4]. Similar health effects have been observed for other gaseous air pollutants such as oxides of nitrogen, volatile organic compounds, and ozone. Although progress has been made over the past decade in reducing exposure to air pollutants, TRAP and other sources of air pollutants (eg, repeated wildfire smoke exposure due to climate change) still pose substantial risks to public health and the environment.
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影响因子：
3.5
作者：
通讯作者：
--
影响因子：
4.5
作者：
Morales-Rubio, Russell;Amador-Munoz, Omar;De Vizcaya-Ruiz, Andrea
通讯作者：
De Vizcaya-Ruiz, Andrea
DOI：
10.1016/j.jaci.2015.10.021
发表时间：
2016-03
期刊：
The Journal of allergy and clinical immunology
影响因子：
--
作者：
Somineni HK;Zhang X;Biagini Myers JM;Kovacic MB;Ulm A;Jurcak N;Ryan PH;Khurana Hershey GK;Ji H
通讯作者：
Ji H
影响因子：
3.3
作者：
Kurt OK;Zhang J;Pinkerton KE
通讯作者：
Pinkerton KE
影响因子：
4.7
作者：
Zhang, Xiaoyu;Zhang, Jianxin;Zhang, Wencai
通讯作者：
Zhang, Wencai