Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: protocol for a cohort study in Montreal, Canada.
Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: protocol for a cohort study in Montreal, Canada.
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DOI：
10.1136/bmjopen-2021-053245
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发表时间：
2021-07-08
期刊：
影响因子：
2.9
通讯作者：
Quach C
中科院分区：
文献类型：
--
作者：
Zinszer K;McKinnon B;Bourque N;Zahreddine M;Charland K;Papenburg J;Fortin G;Hamelin MÈ;Saucier A;Apostolatos A;Pierce L;Savard-Lamothe A;Carbonneau J;Conrod P;Haley N;Laurin I;Boivin G;De Serres G;Quach C
在传播动态多样化和公共卫生干预措施不断演变的背景下，需要进一步的证据来了解学校和日托对COVID-19传播的贡献。Enfants et COVID-19：Étude de séroprévalence（EnCORE）研究将估计学校和日托儿童和人员中SARS-CoV-2的血清阳性率和血清转化率。此外，该研究还将检查血清阳性率与社会人口学特征以及报告的COVID-19症状和测试之间的关联，并调查健康，生活方式和福祉结果的变化。这项研究包括来自加拿大蒙特利尔四个街区62所学校和日托所的儿童和工作人员。所有在参与学校或日托所就读的2-17岁儿童及其家长以及工作人员都被邀请参加。参与者在基线（2020年10月至2021年3月）和随访（2021年5月至6月）时回答简短的问卷并提供通过干血斑收集的血液样本。资料包括社会人口及家庭特征、报告的COVID-19症状及测试、潜在的COVID-19风险因素及预防措施，以及健康及生活方式信息。使用广义估计方程的逻辑回归将用于估计血清阳性率和血清转换，解释学校一级的聚集性。这项研究得到了蒙特利尔大学（CERSES）和圣贾斯汀大学中心医院的研究伦理委员会的批准。研究结果将有助于我们了解SARS-CoV-2在学校和日托中心的传播情况，并将提供给研究参与者及其家人、学校和公共卫生决策者以及研究界。
Further evidence is needed to understand the contribution of schools and daycares for the spread of COVID-19 in the context of diverse transmission dynamics and continually evolving public health interventions. The Enfants et COVID-19: Étude de séroprévalence (EnCORE) study will estimate the seroprevalence and seroconversion of SARS-CoV-2 among school and daycare children and personnel. In addition, the study will examine associations between seroprevalence and sociodemographic characteristics and reported COVID-19 symptoms and tests, and investigates changes in health, lifestyle and well-being outcomes. This study includes children and personnel from 62 schools and daycares in four neighbourhoods in Montreal, Canada. All children aged 2–17 years attending one of the participating schools or daycares and their parents are invited to participate, as well as a sample of personnel members. Participants respond to brief questionnaires and provide blood samples, collected via dried blood spot, at baseline (October 2020–March 2021) and follow-up (May–June 2021). Questionnaires include sociodemographic and household characteristics, reported COVID-19 symptoms and tests, potential COVID-19 risk factors and prevention efforts and health and lifestyle information. Logistic regression using generalised estimating equations will be used to estimate seroprevalence and seroconversion, accounting for school-level clustering. This study was approved by the research ethics boards of the Université de Montréal (CERSES) and the Centre Hospitalier Universitaire Sainte-Justine. Results will contribute to our knowledge about SARS-CoV-2 transmission in schools and daycares and will be made available to study participants and their families, school and public health decision-makers and the research community.
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瑞士学校儿童和青少年SARS-COV-2感染的血清阳性和免疫力：设计基于学校的前瞻性队列研究的设计。
影响因子：
4.6
作者：
Ulyte A;Radtke T;Abela IA;Haile SR;Braun J;Jung R;Berger C;Trkola A;Fehr J;Puhan MA;Kriemler S
通讯作者：
Kriemler S
影响因子：
26.1
作者：
Tönshoff B;Müller B;Elling R;Renk H;Meissner P;Hengel H;Garbade SF;Kieser M;Jeltsch K;Grulich-Henn J;Euler J;Stich M;Chobanyan-Jürgens K;Zernickel M;Janda A;Wölfle L;Stamminger T;Iftner T;Ganzenmueller T;Schmitt C;Görne T;Laketa V;Olberg S;Plaszczyca A;Cortese M;Bartenschlager R;Pape C;Remme R;Huzly D;Panning M;Weigang S;Giese S;Ciminski K;Ankerhold J;Kochs G;Schwemmle M;Handgretinger R;Niemeyer CM;Engel C;Kern WV;Hoffmann GF;Franz AR;Henneke P;Debatin KM;Kräusslich HG
通讯作者：
Kräusslich HG
影响因子：
168.9
作者：
Stringhini, Silvia;Wisniak, Ania;Guessous, Idris
通讯作者：
Guessous, Idris
DOI：
10.1101/2020.06.06.20120857v1.full
发表时间：
2020-10-23
影响因子：
33.9
作者：
Rossen, Lauren M.;Branum, Amy M.;Anderson, Robert N.
通讯作者：
Anderson, Robert N.
影响因子：
--
作者：
Spitzer, Robert L.;Kroenke, Kurt;Loewe, Bernd
通讯作者：
Loewe, Bernd