Prevalence of kidney stones in the United States.
Prevalence of kidney stones in the United States.
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DOI：
10.1016/j.eururo.2012.03.052
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发表时间：
2012-07
期刊：
影响因子：
23.4
通讯作者：
Saigal, Christopher S.
中科院分区：
文献类型：
--
作者：
Scales, Charles D., Jr.;Smith, Alexandria C.;Hanley, Janet M.;Saigal, Christopher S.
上一次对美国肾结石患病率的全国代表性评估发生在1994年。经过13年的中断，国家健康和营养检查调查（NHANES）重新开始收集有关肾结石病史的数据。描述目前结石病在美国的流行情况，并确定与肾结石病史相关的因素。对2007-2010年NHANES（n = 12 110）的响应进行了横断面分析。自报肾结石病史。计算患病率百分比，并使用多变量模型来确定与肾结石病史相关的因素。肾结石的患病率为8.8%（95%置信区间[CI]，8.1-9.5）。男性结石患病率为10.6%（95%CI，9.4-11.9），女性为7.1%（95%CI，6.4-7.8）。肾结石在肥胖人群中比在正常体重人群中更常见（分别为11.2% [95%CI，10.0-12.3]和6.1% [95%CI，4.8-7.4]; p < 0.001）。黑人、非西班牙裔和西班牙裔个体报告结石病史的可能性低于白色、非西班牙裔个体（黑人、非西班牙裔：比值比[OR]：0.37 [95%CI，0.28-0.49]，p < 0.001;西班牙裔：OR：0.60 [95%CI，0.49-0.73]，p < 0.001）。在多变量模型中，肥胖和糖尿病与肾结石病史密切相关。横断面调查设计限制了对肾结石潜在危险因素的因果推断。肾结石在美国影响大约1/11的人。这些数据表明，与NHANES III队列相比，结石病显著增加，特别是在黑人，非西班牙裔和西班牙裔个体中。饮食和生活方式因素可能在肾结石流行病学的变化中起重要作用。
The last nationally representative assessment of kidney stone prevalence in the United States occurred in 1994. After a 13-yr hiatus, the National Health and Nutrition Examination Survey (NHANES) reinitiated data collection regarding kidney stone history. Describe the current prevalence of stone disease in the United States, and identify factors associated with a history of kidney stones. A cross-sectional analysis of responses to the 2007–2010 NHANES (n = 12 110). Self-reported history of kidney stones. Percent prevalence was calculated and multivariable models were used to identify factors associated with a history of kidney stones. The prevalence of kidney stones was 8.8% (95% confidence interval [CI], 8.1–9.5). Among men, the prevalence of stones was 10.6% (95% CI, 9.4–11.9), compared with 7.1% (95% CI, 6.4–7.8) among women. Kidney stones were more common among obese than normal-weight individuals (11.2% [95% CI, 10.0–12.3] compared with 6.1% [95% CI, 4.8–7.4], respectively; p < 0.001). Black, non-Hispanic and Hispanic individuals were less likely to report a history of stone disease than were white, non-Hispanic individuals (black, non-Hispanic: odds ratio [OR]: 0.37 [95% CI, 0.28–0.49], p < 0.001; Hispanic: OR: 0.60 [95% CI, 0.49–0.73], p < 0.001). Obesity and diabetes were strongly associated with a history of kidney stones in multivariable models. The cross-sectional survey design limits causal inference regarding potential risk factors for kidney stones. Kidney stones affect approximately 1 in 11 people in the United States. These data represent a marked increase in stone disease compared with the NHANES III cohort, particularly in black, non-Hispanic and Hispanic individuals. Diet and lifestyle factors likely play an important role in the changing epidemiology of kidney stones.
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作者：
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