SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients.
SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients.
复制标题
DOI:
10.1038/s41598-022-13008-4
复制
发表时间:
2022-05-30
影响因子:
4.6
通讯作者:
中科院分区:
文献类型:
--
作者:
Knowledge about contagiousness is key to accurate management of hospitalized COVID-19 patients. Epidemiological studies suggest that in addition to transmission through droplets, aerogenic SARS-CoV-2 transmission contributes to the spread of infection. However, the presence of virus in exhaled air has not yet been sufficiently demonstrated. In pandemic situations low tech disposable and user-friendly bedside devices are required, while commercially available samplers are unsuitable for application in patients with respiratory distress. We included 49 hospitalized COVID-19 patients and used a disposable modular breath sampler to measure SARS-CoV-2 RNA load in exhaled air samples and compared these to SARS-CoV-2 RNA load of combined nasopharyngeal throat swabs and saliva. Exhaled air sampling using the modular breath sampler has proven feasible in a clinical COVID-19 setting and demonstrated viral detection in 25% of the patients.
登录
查看更多内容
影响因子:
11.8
作者:
Tang, Song;Mao, Yixin;Shi, Xiaoming
通讯作者:
Shi, Xiaoming
影响因子:
15.9
作者:
Lakdawala SS;Menachery VD
通讯作者:
Menachery VD
影响因子:
3.1
作者:
de Oliveira CM;Brochi L;Scarpelli LC;Lopes ACW;Levi JE
通讯作者:
Levi JE
影响因子:
28.3
作者:
Port, Julia R.;Yinda, Claude Kwe;Munster, Vincent J.
通讯作者:
Munster, Vincent J.
影响因子:
16.6
作者:
Richard, Mathilde;Kok, Adinda;Herfst, Sander
通讯作者:
Herfst, Sander