Drivers and modulators in the central auditory pathways.
Drivers and modulators in the central auditory pathways.
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DOI：
10.3389/neuro.01.014.2010
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发表时间：
2010-04-15
影响因子：
4.3
通讯作者：
Sherman SM
中科院分区：
文献类型：
--
作者：
Lee CC;Sherman SM
听觉信息流的经典观点描绘了一个简单的串行路线，从外周通过脑干、中脑和丘脑中的音调组织核团，最终上升到新皮层。然而，复杂的这一画面是许多平行的上升和下降的途径，其在听觉处理的作用是不明确的。为了解决这种模糊性，我们已经确定了几个解剖和生理特性，区分成两组，我们称之为“司机”和“调制器”的听觉神经元通路。驱动通路与信息承载通路相关，而调节通路则修改这些主要信息流。这些属性照亮了一些以前定义不清的听觉通路的潜在作用，并可以进一步扩展到分类未知或错误表征的整个听觉系统的通路。
The classic view of auditory information flow depicts a simple serial route from the periphery through tonotopically-organized nuclei in the brainstem, midbrain and thalamus, ascending eventually to the neocortex. Yet, complicating this picture are numerous parallel ascending and descending pathways, whose roles in auditory processing are poorly defined. To address this ambiguity, we have identified several anatomical and physiological properties that distinguish the auditory glutamatergic pathways into two groups that we have termed “drivers” and “modulators”. Driver pathways are associated with information-bearing pathways, while modulator pathways modify these principal information streams. These properties illuminate the potential roles of some previously ill-defined auditory pathways, and may be extended further to categorize either unknown or mischaracterized pathways throughout the auditory system.
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影响因子：
3.7
作者：
Lee, CC;Imaizumi, K;Winer, JA
通讯作者：
Winer, JA
影响因子：
2.5
作者：
FAMIGLIETTI, EV;PETERS, A
通讯作者：
PETERS, A
影响因子：
3.7
作者：
Felleman, Daniel J.;Van Essen, David C.
通讯作者：
Van Essen, David C.
影响因子：
2.5
作者：
HAMOS, JE;VANHORN, SC;SHERMAN, SM
通讯作者：
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影响因子：
3
作者：
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通讯作者：
Sherman, S. Murray