Clear castable polyurethane elastomer for fabrication of microfluidic devices.

Clear castable polyurethane elastomer for fabrication of microfluidic devices.
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清除可铸的聚氨酯弹性体,用于制造微流体设备。

DOI:
10.1039/c3lc50558h
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发表时间:
2013-10-07
期刊:
影响因子:
6.1
通讯作者:
Ingber DE
Ingber DE
中科院分区:
工程技术1区
文献类型:
--
作者:
Domansky K;Leslie DC;McKinney J;Fraser JP;Sliz JD;Hamkins-Indik T;Hamilton GA;Bahinski A;Ingber DE

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聚二甲基硅氧烷(PDMS)具有用于制造微流体装置的许多期望的性质,包括光学透明性、柔性、生物相容性和通过浇铸的制造;然而,将小疏水分子分配到PDMS的本体中阻碍了PDMS微流体装置用于化学加工和药物开发应用的工业接受。在这里,我们描述了一种有吸引力的替代材料,它在光学透明度,柔韧性和可铸性方面与PDMS相似,但也能抵抗小疏水分子的吸收。
Polydimethylsiloxane (PDMS) has numerous desirable properties for fabricating microfluidic devices, including optical transparency, flexibility, biocompatibility, and fabrication by casting; however, partitioning of small hydrophobic molecules into the bulk of PDMS hinders industrial acceptance of PDMS microfluidic devices for chemical processing and drug development applications. Here we describe an attractive alternative material that is similar to PDMS in terms of optical transparency, flexibility and castability, but that is also resistant to absorption of small hydrophobic molecules.
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