Dmrt genes in the development and evolution of sexual dimorphism.
Dmrt genes in the development and evolution of sexual dimorphism.
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DOI:
10.1016/j.tig.2012.02.002
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发表时间:
2012-04
影响因子:
11.4
通讯作者:
Kopp, Artyom
中科院分区:
文献类型:
--
作者:
Kopp, Artyom
Most animals are sexually dimorphic, yet different taxa have different sex-specific traits. Despite major differences in the genetic control of sexual development among animal lineages, the Dmrt family of transcription factors has been shown to be involved in sex-specific differentiation in all animals studied so far. In recent years, the functions of Dmrt genes have been characterized in many animal groups, opening the way for a broad comparative perspective. In this review, I focus on the similarities and differences in the functions of Dmrt genes across the animal kingdom. I highlight a number of common themes in the sexual development of different taxa, discuss how Dmrt genes have acquired new roles during animal evolution, and show how they contributed to the origin of novel sex-specific traits.
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