Phylogenetic analysis of the Y-chromosome haplogroup C2b-F1067, a dominant paternal lineage in Eastern Eurasia
Phylogenetic analysis of the Y-chromosome haplogroup C2b-F1067, a dominant paternal lineage in Eastern Eurasia
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Y 染色体单倍群 C2b-F1067（欧亚大陆东部的显性父系谱系）的系统发育分析
DOI：
10.1038/s10038-020-0775-1
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发表时间：
2020-05
影响因子：
3.5
通讯作者：
Wei Lan-Hai
中科院分区：
文献类型：
--
作者：
Wu Qiao;Cheng Hui-Zhen;Sun Na;Ma Peng-Cheng;Sun Jin;Yao Hong-Bing;Xie Yong-Mei;Li Yong-Lan;Meng Song-Lin;Zhabagin Maxat;Cai Yan-Huan;Lu Da-Ru;Yan Shi;Wei Lan-Hai
人类Y染色体单倍群C2B-F1067是欧亚大陆东部人群的父系优势家系之一。为了探索这个单倍群的起源、多样性和扩展，我们从C2B-F1067男性中产生了206个新的Y染色体序列，并共同分析了这个单倍群的220个Y染色体序列。用Beast软件重建了C2B-F1067单倍群的系统发育树，并进行了年龄估计。修订后的C2B-F1067的系统发育包括155个亚系，1986个非私人变种和>；6000个私人变种。年龄估算表明，C2B-F1067的初始分裂发生在约32.8千年前(Kya)，该单群的主要亚系在最近1万年经历了持续的扩张。我们确定了许多几乎特定于中国中的朝鲜族、蒙古族、中国人和其他少数民族的亚语系。特别是，我们评估了大炎汗家族和孔子家族的特定候选谱系，这两个家族是中国商朝统治家族的后代。这些发现表明，具有不同C2B-F1067亚系的古代种群在欧亚大陆东部大多数现代种群的形成过程中发挥了重要作用，并最终成为这些种群的父系起源。
Human Y-chromosome haplogroup C2b-F1067 is one of the dominant paternal lineages of populations in Eastern Eurasia. In order to explore the origin, diversification, and expansion of this haplogroup, we generated 206 new Y-chromosome sequences from C2b-F1067 males and coanalyzed 220 Y-chromosome sequences of this haplogroup. BEAST software was used to reconstruct a revised phylogenetic tree of haplogroup C2b-F1067 with age estimates. The revised phylogeny of C2b-F1067 included 155 sublineages, 1986 non-private variants, and >6000 private variants. The age estimation suggested that the initial splitting of C2b-F1067 happened at about 32.8 thousand years ago (kya) and the major sublineages of this haplgroup experienced continuous expansion in the most recent 10,000 years. We identified numerous sublineages that were nearly specific for Korean, Mongolian, Chinese, and other ethnic minorities in China. In particular, we evaluated the candidate-specific lineage for the Dayan Khan family and the Confucius family, the descendants of the ruling family of the Chinese Shang dynasty. These findings suggest that ancient populations with varied C2b-F1067 sublineages played an important role during the formation of most modern populations in Eastern Eurasia, and thus eventually became the founding paternal lineages of these populations.
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影响因子：
64.8
作者：
Mallick, Swapan;Li, Heng;Lipson, Mark;Mathieson, Iain;Gymrek, Melissa;Racimo, Fernando;Zhao, Mengyao;Chennagiri, Niru;Nordenfelt, Susanne;Tandon, Arti;Skoglund, Pontus;Lazaridis, Iosif;Sankararaman, Sriram;Fu, Qiaomei;Rohland, Nadin;Renaud, Gabriel;Erlich, Yaniv;Willems, Thomas;Gallo, Carla;Spence, Jeffrey P.;Song, Yun S.;Poletti, Giovanni;Balloux, Francois;van Driem, George;de Knijff, Peter;Romero, Irene Gallego;Jha, Aashish R.;Behar, Doron M.;Bravi, Claudio M.;Capelli, Cristian;Hervig, Tor;Moreno-Estrada, Andres;Posukh, Olga L.;Balanovska, Elena;Balanovsky, Oleg;Karachanak-Yankova, Sena;Sahakyan, Hovhannes;Toncheva, Draga;Yepiskoposyan, Levon;Tyler-Smith, Chris;Xue, Yali;Abdullah, M. Syafiq;Ruiz-Linares, Andres;Beall, Cynthia M.;Di Rienzo, Anna;Jeong, Choongwon;Starikovskaya, Elena B.;Metspalu, Ene;Parik, Juri;Villems, Richard;Henn, Brenna M.;Hodoglugil, Ugur;Mahley, Robert;Sajantila, Antti;Stamatoyannopoulos, George;Wee, Joseph T. S.;Khusainova, Rita;Khusnutdinova, Elza;Litvinov, Sergey;Ayodo, George;Comas, David;Hammer, Michael F.;Kivisild, Toomas;Klitz, William;Winkler, Cheryl A.;Labuda, Damian;Bamshad, Michael;Jorde, Lynn B.;Tishkoff, Sarah A.;Watkins, W. Scott;Metspalu, Mait;Dryomov, Stanislav;Sukernik, Rem;Singh, Lalji;Thangaraj, Kumarasamy;Paeaebo, Svante;Kelso, Janet;Patterson, Nick;Reich, David
通讯作者：
Reich, David
大数据中心：从沉积到集成再到转换。
影响因子：
14.9
作者：
BIG Data Center Members
通讯作者：
BIG Data Center Members
DOI：
10.1017/chol9780521470308
发表时间：
1999
期刊：
--
影响因子：
--
作者：
M. Loewe;Edward L. Shaughnessy
通讯作者：
M. Loewe;Edward L. Shaughnessy
影响因子：
7
作者：
A. Redd
通讯作者：
A. Redd
Y染色体单倍群C的全球分布揭示了非洲出逃和东亚早期定居的史前迁徙路线
影响因子：
3.5
作者：
Zhong, Hua;Shi, Hong;Su, Bing
通讯作者：
Su, Bing