Ectopic pregnancy in China during 2011-2020: a single-centre retrospective study of 9499 cases.
Ectopic pregnancy in China during 2011-2020: a single-centre retrospective study of 9499 cases.
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DOI：
10.1186/s12884-022-05269-8
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发表时间：
2022-12-10
影响因子：
3.1
通讯作者：
中科院分区：
文献类型：
--
作者：
既往研究表明，异位妊娠（EP）在我国的发病率呈上升趋势。但在中国人口老龄化和生育率下降的背景下，实施普遍两孩政策后EP的发病率是否发生了变化，目前尚不清楚。从医院电子病历中收集2011年1月至2020年12月的EP数据，包括每年的分娩次数，剖腹产率，异位妊娠，输卵管妊娠的治疗以及平均费用和住院时间。分析了EP发病率的趋势，并使用连接点回归分析计算了年百分比变化（APC）。共收集到9499例EP病例，其中剖宫产瘢痕妊娠（CSP）占第二位（6.73%）。每100例分娩的EP呈下降趋势，从2011年的7.60%下降到2020年的4.28%，APC为-1.87（P < 0.05）。尤其是在实施普遍两孩政策后，孕产妇年龄有所提高。高龄产妇（≥ 35岁）的构成比和剖宫产率也有所增加，但CSP没有增加。腹腔镜输卵管切除术是主要的手术方式，开腹手术和腹腔镜输卵管造口术的采用逐年减少。虽然在本研究条件下未观察到二孩政策对EP的明显影响，但政策实施后EP尤其是高龄妇女EP的变化需要进一步评估。剖宫产率的降低有利于降低剖宫产率。
Previous studies have shown that the incidence of ectopic pregnancy (EP) is increasing in China. It is unclear, however, whether the incidence of EP has changed after the implementation of the universal two-child policy in the context of China’s aging population and declining fertility rate. Data concerning EP from January 2011 to December 2020 were collected from the hospital’s electronic medical records, which included the annual number of delivery, caesarean section rate, ectopic pregnancies, treatment of tubal pregnancy, and average costs and length of hospitalization. Trends of the EP incidence were analysed and annual percentage change (APC) was calculated using connected point regression analyses. A total of 9499 cases of EP were collected, among which caesarean scar pregnancy (CSP) accounts for the second highest (6.73%). The EP per 100 deliveries revealed a downward trend, from 7.60% in 2011 to 4.28% in 2020 with an APC of -1.87 (P < 0.05). The maternal age was increased, especially after the implementation of the universal two-child policy. The constituent ratio for the advanced maternal age (≥ 35) and the caesarean section rate, but not the CSP, were also increased. Laparoscopic salpingectomy was the main surgical method, whereas the adoption of laparotomy and laparoscopic salpingostomy was decreasing year by year. Although no obvious effect of the two-child policy on EP has been observed under the conditions of this study, the change in EP especially in advanced-age women after the policy implementation needs further evaluation. A decreased caesarean section rate, in primipara is beneficial to reducing the CSP.
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影响因子：
3.4
作者：
Li XL;Du DF;Chen SJ;Zheng SH;Lee AC;Chen Q
通讯作者：
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DOI：
10.1111/1471-0528.15255
发表时间：
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影响因子：
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作者：
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影响因子：
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通讯作者：
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影响因子：
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作者：
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影响因子：
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作者：
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