Development of a high resolution voxelised head phantom for medical physics applications.
Development of a high resolution voxelised head phantom for medical physics applications.
复制标题
DOI：
10.1016/j.ejmp.2017.01.007
复制
发表时间：
2017-01
期刊：
影响因子：
--
通讯作者：
Schulte RW
中科院分区：
文献类型：
--
作者：
Giacometti V;Guatelli S;Bazalova-Carter M;Rosenfeld AB;Schulte RW
计算拟人模型已成为医学成像和放射治疗剂量学以及辐射防护的重要研究工具。具有真实解剖特征的计算体模的发展对医学物理学新方法的发展做出了重要贡献。对于许多应用，期望这样的计算幻影具有真实世界的物理对应物，以便验证所获得的结果。在这项工作中，我们报告了一个体素化的幻影，HIGH_RES_HEAD，建模儿科头部的商业幻影715-HN（CIRS）的基础上的发展。HIGH_RES_HEAD因其解剖细节和高空间分辨率（0.18 × 0.18 mm 2像素大小）而独特。这种体模的开发是为了研究新的质子计算机断层扫描（pCT）系统在探测器技术和图像重建算法方面的性能。HIGH_RES_HEAD用于pCT系统的ad-hoc Geant 4模拟建模。模拟应用程序先前验证的实验结果。当与相同儿科头部的标准空间分辨率体素化体模相比时，结果表明，在pCT重建研究中，HIGH_RES_HEAD的使用转化为实验结果和模拟结果之间的平均相对阻止能力差异从2%降低到0.7%，从而提高了头部体模模拟的整体质量。HIGH_RES_HEAD也可用于其他医学物理应用，如治疗计划研究。创建了体素化体模的第二个版本，其中包含颅骨肿瘤和周围危险器官的原型基底。
Computational anthropomorphic phantoms have become an important investigation tool for medical imaging and dosimetry for radiotherapy and radiation protection. The development of computational phantoms with realistic anatomical features contribute significantly to the development of novel methods in medical physics. For many applications, it is desirable that such computational phantoms have a real-world physical counterpart in order to verify the obtained results. In this work, we report the development of a voxelised phantom, the HIGH_RES_HEAD, modelling a paediatric head based on the commercial phantom 715-HN (CIRS). HIGH_RES_HEAD is unique for its anatomical details and high spatial resolution (0.18 × 0.18 mm2 pixel size). The development of such a phantom was required to investigate the performance of a new proton computed tomography (pCT) system, in terms of detector technology and image reconstruction algorithms. The HIGH_RES_HEAD was used in an ad-hoc Geant4 simulation modelling the pCT system. The simulation application was previously validated with respect to experimental results. When compared to a standard spatial resolution voxelised phantom of the same paediatric head, it was shown that in pCT reconstruction studies, the use of the HIGH_RES_HEAD translates into a reduction from 2% to 0.7% of the average relative stopping power difference between experimental and simulated results thus improving the overall quality of the head phantom simulation. The HIGH_RES_HEAD can also be used for other medical physics applications such as treatment planning studies. A second version of the voxelised phantom was created that contains a prototypic base of skull tumour and surrounding organs at risk.
登录
查看更多内容
影响因子：
1.8
作者：
Johnson RP;Bashkirov V;DeWitt L;Giacometti V;Hurley RF;Piersimoni P;Plautz TE;Sadrozinski HF;Schubert K;Schulte R;Schultze B;Zatserklyaniy A
通讯作者：
Zatserklyaniy A
DOI：
10.1016/j.nima.2012.04.029
发表时间：
2013-01-21
期刊：
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment
影响因子：
--
作者：
Sadrozinski HF;Johnson RP;Macafee S;Plumb A;Steinberg D;Zatserklyaniy A;Hurley VB;Schulte R
通讯作者：
Schulte R
影响因子：
3.5
作者：
Schuemann, J.;Paganetti, H.;Perl, J.
通讯作者：
Perl, J.
影响因子：
3.5
作者：
Xu XG
通讯作者：
Xu XG
影响因子：
3.5
作者：
Caon, M;Bibbo, G;Pattison, J
通讯作者：
Pattison, J