Inflammation and pregnancy: the role of the immune system at the implantation site.

Inflammation and pregnancy: the role of the immune system at the implantation site.
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DOI:
10.1111/j.1749-6632.2010.05938.x
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发表时间:
2011-03
影响因子:
5.2
通讯作者:
Guller S
Guller S
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Mor G;Cardenas I;Abrahams V;Guller S

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The concept that pregnancy is associated with immune suppression has created a myth of pregnancy as a state of immunological weakness and, therefore, of increased susceptibility to infectious diseases. A challenging question is whether the maternal immune system is a friend or a foe of pregnancy. In this review, we discuss data associated to the role of the immune system during pregnancy. We propose a new paradigm in terms of the fetal-maternal immune interaction as well as the immunological response of the mother to micro-organism. Our challenge is to better understand the immunology of pregnancy in order to deliver the appropriate treatment to patients with pregnancy complications as well as to determine public policies for the protection of pregnant women during pandemics.
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发表时间: 2004-04-01
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