Imaging organelle membranes in live cells at the nanoscale with lipid-based fluorescent probes.
Imaging organelle membranes in live cells at the nanoscale with lipid-based fluorescent probes.
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DOI：
10.1016/j.cbpa.2021.09.003
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发表时间：
2021-12
影响因子：
7.8
通讯作者：
中科院分区：
文献类型：
--
作者：
Understanding how organelles interact, exchange materials, assemble, disassemble, and evolve as a function of space, time, and environment is an exciting area at the very forefront of chemical and cell biology. Here, we bring attention to recent progress in the design and application of lipid-based tools to visualize and interrogate organelles in live cells, especially at super resolution. We highlight strategies that rely on modification of natural lipids or lipid-like small molecules ex cellula, where organelle specificity is provided by the structure of the chemically modified lipid, or in cellula using cellular machinery, where an enzyme labels the lipid in situ. We also describe recent improvements to the chemistry upon which lipid probes rely, many of which have already begun to broaden the scope of biological questions that can be addressed by imaging organelle membranes at the nanoscale.
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影响因子：
15
作者：
Blackman, Melissa L.;Royzen, Maksim;Fox, Joseph M.
通讯作者：
Fox, Joseph M.
影响因子：
7.8
作者：
GRIFFITHS, G;PFEIFFER, S;SIMONS, K;MATLIN, K
通讯作者：
MATLIN, K
DOI：
10.1073/pnas.1903949116
发表时间：
2019-07-30
影响因子：
11.1
作者：
Liang, Dongjun;Wu, Kane;Baskin, Jeremy M.
通讯作者：
Baskin, Jeremy M.
影响因子：
16.6
作者：
Danylchuk, Dmytro, I;Moon, Seonah;Klymchenko, Andrey S.
通讯作者：
Klymchenko, Andrey S.
影响因子：
48
作者：
Grimm JB;Muthusamy AK;Liang Y;Brown TA;Lemon WC;Patel R;Lu R;Macklin JJ;Keller PJ;Ji N;Lavis LD
通讯作者：
Lavis LD