Do Neighborhood Factors Modify the Effects of Lead Exposure on Child Behavior?
Do Neighborhood Factors Modify the Effects of Lead Exposure on Child Behavior?
复制标题
邻里因素是否会改变铅暴露对儿童行为的影响？
DOI：
10.3390/toxics10090517
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发表时间：
2022-08-31
期刊：
影响因子：
4.6
通讯作者：
Kordas K
中科院分区：
文献类型：
--
作者：
Frndak S;Barg G;Queirolo EI;Mañay N;Colder C;Yu G;Ahmed Z;Kordas K
铅暴露和社区会影响儿童的行为，但尚不清楚社区特征是否会改变铅对行为的影响。理解这些修改具有重要的干预意义。乌拉圭蒙得维的亚儿童(~7岁)的血铅水平被归类为2微克/分升。教师完成两个行为评定量表(n=455)。在为期一年的随访中(n=380)，照顾者报告了儿童发脾气和育儿冲突。多水平广义线性模型以邻里劣势、归一化差异植被指数(NDVI)和到最近绿地的距离为效应修饰符，检验了BLL与行为之间的关联。没有注意到对邻里不利或NDVI的影响修改。与≥为2微克/dL的儿童相比，居住在离绿地最近的BLLS<；2微克/分升的儿童在行为问题量表上的得分较低。当距离绿地最远时，孩子们的行为问题相似，无论BLL是什么。在BLL和≥为2微克/分升的儿童中，每天发脾气和冲突的概率约为20%，而当BLL和LT；2微克/分升最接近绿地时，BLL和BLL儿童的日常发脾气和冲突的概率约为45%。在距离绿地最远的地方，BLL与发脾气和冲突无关。BLL对儿童行为的影响因距离绿地而改变，这表明干预措施应同时考虑绿地准入和铅暴露预防。
Lead exposure and neighborhoods can affect children’s behavior, but it is unclear if neighborhood characteristics modify the effects of lead on behavior. Understanding these modifications has important intervention implications. Blood lead levels (BLLs) in children (~7 years) from Montevideo, Uruguay, were categorized at 2 µg/dL. Teachers completed two behavior rating scales (n = 455). At one-year follow-up (n = 380), caregivers reported child tantrums and parenting conflicts. Multilevel generalized linear models tested associations between BLLs and behavior, with neighborhood disadvantage, normalized difference vegetation index (NDVI), and distance to nearest greenspace as effect modifiers. No effect modification was noted for neighborhood disadvantage or NDVI. Children living nearest to greenspace with BLLs < 2 µg/dL were lower on behavior problem scales compared to children with BLLs ≥ 2 µg/dL. When furthest from greenspace, children were similar on behavior problems regardless of BLL. The probability of daily tantrums and conflicts was ~20% among children with BLLs < 2 µg/dL compared to ~45% among children with BLLs ≥ 2 µg/dL when closest to greenspace. Furthest from greenspace, BLLs were not associated with tantrums and conflicts. Effect modification of BLL on child behavior by distance to greenspace suggests that interventions should consider both greenspace access and lead exposure prevention.
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