Learning to read an alphabet of human faces produces left-lateralized training effects in the fusiform gyrus.
Learning to read an alphabet of human faces produces left-lateralized training effects in the fusiform gyrus.
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学会阅读人脸的字母在梭状回中产生左侧训练效果。
DOI：
10.1162/jocn_a_00506
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发表时间：
2014-04
影响因子：
3.2
通讯作者：
Fiez JA
中科院分区：
文献类型：
--
作者：
Moore MW;Durisko C;Perfetti CA;Fiez JA
许多功能性神经影像学研究表明，大多数正字法刺激，如印刷英语单词，产生左侧的梭状回（FG）内的一个特征性位置称为视觉词形区（VWFA）的反应。我们开发了一个实验字母表（FaceFont），包括35个面孔音素对解开语音和感知的影响，在FG的正字法处理偏侧化。使用功能成像，我们发现，在VWFA附近的区域响应FaceFont字更强烈的训练与未经训练的参与者，而没有差异，观察到在正确的FG。左侧FG区域中的训练反应幅度与行为阅读表现相关，这提供了强有力的证据，即通过训练招募的神经组织支持新获得的阅读技能。这些结果表明，左偏化的正字法处理并不限于特定的视觉感知功能的刺激。相反，偏侧化可能发生，因为VWFA附近的解剖投影提供了视觉系统和参与语音表征的左侧语言区域之间的独特互连。
Numerous functional neuroimaging studies have shown that most orthographic stimuli, such as printed English words, produce a left-lateralized response within the fusiform gyrus (FG) at a characteristic location termed the visual word form area (VWFA). We developed an experimental alphabet (FaceFont) comprising 35 face–phoneme pairs to disentangle phonological and perceptual influences on the lateralization of orthographic processing within the FG. Using functional imaging, we found that a region in the vicinity of the VWFA responded to FaceFont words more strongly in trained versus untrained participants, whereas no differences were observed in the right FG. The trained response magnitudes in the left FG region correlated with behavioral reading performance, providing strong evidence that the neural tissue recruited by training supported the newly acquired reading skill. These results indicate that the left lateralization of the orthographic processing is not restricted to stimuli with particular visual-perceptual features. Instead, lateralization may occur because the anatomical projections in the vicinity of the VWFA provide a unique interconnection between the visual system and left-lateralized language areas involved in the representation of speech.
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影响因子：
2.5
作者：
ARGUIN, M;BUB, DN
通讯作者：
BUB, DN
影响因子：
3.7
作者：
Ben-Shachar, Michal;Dougherty, Robert F.;Wandell, Brian A.
通讯作者：
Wandell, Brian A.
影响因子：
3.7
作者：
Downing, P. E.;Chan, A. W. -Y.;Kanwisher, N.
通讯作者：
Kanwisher, N.
影响因子：
25
作者：
Grill-Spector, K;Knouf, N;Kanwisher, N
通讯作者：
Kanwisher, N
DOI：
10.1006/cbmr.1996.0014
发表时间：
1996-06-01
期刊：
COMPUTERS AND BIOMEDICAL RESEARCH
影响因子：
--
作者：
Cox, RW
通讯作者：
Cox, RW