Post-acute and long-COVID-19 symptoms in patients with mild diseases: a systematic review.
Post-acute and long-COVID-19 symptoms in patients with mild diseases: a systematic review.
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轻度疾病患者的急性后和长期covid-19症状：系统评价。
DOI：
10.1093/fampra/cmab076
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发表时间：
2022-01-19
期刊：
影响因子：
2.2
通讯作者：
van Jaarsveld CHM
中科院分区：
文献类型：
--
作者：
van Kessel SAM;Olde Hartman TC;Lucassen PLBJ;van Jaarsveld CHM
预计全科医生将越来越多地面临一大群患者，这些患者在出现轻度（门诊治疗）COVID-19感染的初始症状后，症状持续三周。目前，对这些持续性症状的研究主要集中在重症感染患者（在住院环境中进行管理），而对轻症患者的研究很少。本系统综述的主要目的是概述轻度COVID-19感染后患者持续症状的性质和频率。于2021年2月2日在Pubmed、Embase和PsychINFO进行系统文献检索。定量研究、定性研究、临床经验和病例报告被认为是合格的设计。本文献综述共纳入9篇文章。轻度COVID-19感染后患者出现持续症状的频率在10%至35%之间。COVID-19轻度感染后持续出现的症状可分为身体症状、精神症状和社交症状。疲劳是最常见的持续性症状。其他经常出现的持续性症状有呼吸困难、咳嗽、胸痛、头痛、精神和认知状态下降以及嗅觉功能障碍。此外，研究发现，轻度COVID-19感染后持续出现的症状可能会对工作和日常功能产生重大影响。已经有一些证据表明，在三分之一的患者中，轻度COVID-19的症状在三周后仍然存在。然而，缺乏3个月（长covid）后症状持续的数据。需要更多的研究来帮助全科医生管理长期covid。
It is expected that GPs are increasingly confronted with a large group of patients with symptoms persisting three weeks after initial symptoms of a mild (managed in the outpatient setting) COVID-19 infection. Currently, research on these persistent symptoms mainly focuses on patients with severe infections (managed in an inpatient setting) whereas patients with mild disease are rarely studied. The main objective of this systematic review was to create an overview of the nature and frequency of persistent symptoms experienced by patients after mild COVID-19 infection. Systematic literature searches were performed in Pubmed, Embase and PsychINFO on 2 February 2021. Quantitative studies, qualitative studies, clinical lessons and case reports were considered eligible designs. In total, nine articles were included in this literature review. The frequency of persistent symptoms in patients after mild COVID-19 infection ranged between 10% and 35%. Symptoms persisting after a mild COVID-19 infection can be distinguished into physical, mental and social symptoms. Fatigue was the most frequently described persistent symptom. Other frequently occurring persistent symptoms were dyspnoea, cough, chest pain, headache, decreased mental and cognitive status and olfactory dysfunction. In addition, it was found that persisting symptoms after a mild COVID-19 infection can have major consequences for work and daily functioning. There is already some evidence that symptoms of mild COVID-19 persist after 3 weeks in a third of patients. However, there is a lack of data about symptoms persisting after 3 months (long-COVID). More research is needed to help GPs in managing long-COVID.
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影响因子：
3.4
作者：
D'Ascanio, Luca;Pandolfini, Manlio;Di Stadio, Arianna
通讯作者：
Di Stadio, Arianna
严重的急性呼吸综合症对身体状况和生活质量的影响。
影响因子：
4.3
作者：
Lau HM;Lee EW;Wong CN;Ng GY;Jones AY;Hui DS
通讯作者：
Hui DS
影响因子：
--
作者：
Kingstone, Tom;Taylor, Anna K;Chew-Graham, Carolyn A
通讯作者：
Chew-Graham, Carolyn A
影响因子：
--
作者：
Hickie, Ian;Davenport, Trace;Lloyd, Andrew
通讯作者：
Lloyd, Andrew
DOI：
10.1177/070674370705200405
发表时间：
2007-04-01
影响因子：
4
作者：
Lee, Antoinette M.;Wong, Josephine G. W. S.;Chua, Siew E.
通讯作者：
Chua, Siew E.